ReviewFrontiers in oncology2025
Relationship between breast tissue involution and breast cancer.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Menopausal timing and senescent-immune coupling in age-related lobular involution of the human breast: a longitudinal cohort study.EBioMedicine · 2026Article
- Molecular Mechanisms Driving Metastatic Progression Within the Aged Tumor Microenvironment.International journal of molecular sciences · 2025Review
- Targeting HER2-Positive HCC1954 Breast Cancer Cells by Novel Thiazole-Dihydrobenzisoxazoles: In-Depth Design, Synthesis and InitialOncology research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast tissue involution is a process in which the epithelial tissue of the mammary gland gradually disappears with age. The relationship between breast tissue involvement and breast cancer (BC) has received increasing amounts of attention in recent years. Many scholars believe that breast tissue involution is a significant risk factor for BC. Breast imaging parameters, particularly mammographic density (MD), may indirectly reflect the degree of breast tissue involution, which may provide a solid basis for classifying priority screening groups for BC. This review explored the relationship between breast tissue involution and BC by providing an overview of breast tissue involution and elaborating on the association between MD and BC. Consistent with the results of other studies, women with complete breast tissue involution had a lower risk of BC, whereas women with a high MD had a relatively greater risk of BC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.