Evidence map›Paper›PMID 40260257›Full record

ArticleFrontiers in immunology2025

Case Report: Maribavir for refractory cytomegalovirus viremia after renal transplantation in a child with Schimke's immune-osseous dysplasia.

Jia-Shuan Huang, Hong-Kai Wang, Li-Ping Rong, Xiao-Yun Jiang, Long-Shan Liu, Liu-Yi Huang, Na Zhang, Zhi-Hui Yue

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia-Shuan HuangPediatrics Department, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Hong-Kai WangMedical College, Sun Yat-Sen University, Guangzhou, China.
Li-Ping RongPediatrics Department, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Xiao-Yun JiangPediatrics Department, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Long-Shan LiuOrgan Transplantation Department, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Liu-Yi HuangPediatrics Department, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Na ZhangPediatrics Department, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Zhi-Hui YuePediatrics Department, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) is a major opportunistic pathogen in recipients of solid organ transplantation. Maribavir, a pUL97 protein kinase inhibitor, was approved for the treatment of refractory post-transplant CMV infection in the US in 2021. However, it is rarely used in pediatric patients worldwide. Here, we report the case of a Chinese boy with Schimke's immune-osseous dysplasia (SIOD) who developed refractory CMV infection after a renal transplantation. An 11-year-old boy was hospitalized with recurrent abdominal and testicular pain 50 days after renal transplantation. Diagnoses included urinary tract infection, epididymitis, CMV viremia, stage 2 chronic kidney disease, and SIOD. After five days of treatment, his pain improved, but he developed persistent fever and shortness of breath. Blood CMV levels rose to 1.64 × 10

Indexed as

Antiviral AgentsBenzimidazolesCytomegalovirusCytomegalovirus InfectionsImmunologic Deficiency SyndromesKidney TransplantationOsteochondrodysplasiasPrimary Immunodeficiency DiseasesRibonucleosidesViremiaArteriosclerosisChildDichlororibofuranosylbenzimidazoleHumansMaleNephrotic SyndromeAntiviral AgentsBenzimidazolesDichlororibofuranosylbenzimidazolemaribavirRibonucleosideschildrenCMVcytomegalovirus GCVrenal transplantSchimke’s immune-osseous dysplasia

Identifiers

PMID40260257
PMCPMC12009931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.