Evidence map›Paper›PMID 40260193›Full record

ArticlePeerJ2025

Occult zonulopathy detected during cataract surgery in patients with acute primary angle closure: a retrospective study.

Jiawei Chen, Xiang-Ling Yuan, Xinyue Zhang, Yanjun Huang, Xiaona Huang, Xuanchu Duan

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Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jiawei ChenAier Academy of Ophthalmology, Central South University, Changsha, Hunan, China.
Xiang-Ling YuanAier Academy of Ophthalmology, Central South University, Changsha, Hunan, China.
Xinyue ZhangAier Academy of Ophthalmology, Central South University, Changsha, Hunan, China.
Yanjun HuangDepartment of Ophthalmology, The Sixth Affiliated Hospital of South China University of Technology, Foshan, Guangdong, China.
Xiaona HuangDepartment of Ophthalmology, The Sixth Affiliated Hospital of South China University of Technology, Foshan, Guangdong, China.
Xuanchu DuanAier Academy of Ophthalmology, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Whether occult zonulopathy contributes to the development of acute primary angle closure (APAC) remains elusive. This study aimed to determine the association between occult zonulopathy detected during cataract surgery and APAC and to investigate the biometric characteristics of APAC patients with or without occult zonulopathy. Methods: Retrospective case-control study. A total of 27 Chinese unilateral APAC subjects and 132 control subjects with comprehensive ophthalmic examinations were recruited. Occult zonulopathy was identified with the intraoperative signs during cataract surgery. The proportion of occult zonulopathy was compared between the APAC and control groups. A multivariate logistic analysis was conducted to determine the association between occult zonulopathy and APAC. The ocular biometric parameters were compared between APAC and the contralateral eyes in APAC patients with or without occult zonulopathy. Results: APAC patients (63.0%) had a significantly larger proportion of occult zonulopathy than control subjects (1.5%, Conclusion: A larger proportion of occult zonulopathy was significantly associated with APAC. Occult zonulopathy could be a risk factor for APAC by inducing forward shifting of the lens.

Indexed as

Cataract ExtractionGlaucoma, Angle-ClosureAgedCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsAcute primary angle closureBiometric parametersLens positionOccult zonulopathy

Identifiers

PMID40260193
PMCPMC12010992

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.