Evidence map›Paper›PMID 40260181›Full record

ArticleJournal of pain management and therapeutic care2024

Initial Experience with Bupivacaine-Meloxicam Extended Formulation (Zynrelef

C J Staniorski, A Madhavaram, D Sharbaugh, A Watts, R V Vasan, V N Pena, A M Quinn, J M Myrga, Y Krampe, J G Yabes and 3 more

Abstract read
In one paragraph

Article in Journal of pain management and therapeutic care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

C J StaniorskiDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
A MadhavaramSchool of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
D SharbaughDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
A WattsDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
R V VasanDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
V N PenaDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
A M QuinnDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
J M MyrgaDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Y KrampeDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
J G YabesDivision of internal Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
J E ChellyDepa1tment of Anesthesiology and Perioperative Medicine and Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
B J DaviesDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
B L JacobsDivision of Health Services Research, Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Funding

Reduction of opioid requirement associated with Auriculo-nerve stimulation following open surgeryR01DA054513 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHELLY, JACQUES E., SADHASIVAM, SENTHILKUMAR · 2022 to 2025
$2.1M
NIDA NIH HHS R01 DA054513
6 · The paper itself

Abstract

Introduction: The opioid epidemic has led to efforts to improve peri-operative pain control by using multiple modalities. The goal of this study was to evaluate the efficacy and safety of bupivacaine meloxicam extended formulation (Zynrelef Materials and Methods: Patients who received Zynrelef Results: A total of 116 patients were included, 44 of whom received Zynrelef Conclusions: Zynrelef

Indexed as

Extended-Release Bupivacaine Meloxicam Drug CombinationMultimodal AnalgesiaNephrectomyProstatectomyUrogenital Neoplasms

Identifiers

PMID40260181
PMCPMC12010834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.