Evidence map›Paper›PMID 40260132›Full record

ReviewClinicoEconomics and outcomes research : CEOR2025

Comprehensive Insights into the Economic Burden of Rheumatoid Arthritis in Latin America: A Systematic Literature Review of Regional Perspectives.

Angela Isabel Maldonado-Restrepo, Gabriel E Acelas-Gonzalez, Gabriel-Santiago Rodríguez-Vargas, Pedro Rodriguez-Linares, Javier-Leonardo Gonzalez-Rodriguez, Adriana Rojas-Villarraga, Pedro Santos-Moreno

Abstract readReview
In one paragraph

Review in ClinicoEconomics and outcomes research : CEOR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angela Isabel Maldonado-RestrepoSchool of Management and Business, Research Group Management and Business, Universidad del Rosario, Bogotá, Colombia.
Gabriel E Acelas-GonzalezResearch Vicerectory, Fundación Universitaria de Ciencias de la Salud - FUCS, Bogotá, Colombia.ORCID 0000-0002-0906-7557
Gabriel-Santiago Rodríguez-VargasResearch Department, Biomab - Center for Rheumatoid Arthritis, Bogotá, Colombia.ORCID 0000-0003-1613-7100
Pedro Rodriguez-LinaresResearch Department, Biomab - Center for Rheumatoid Arthritis, Bogotá, Colombia.ORCID 0000-0002-3319-2577
Javier-Leonardo Gonzalez-RodriguezSchool of Management and Business, Research Group Management and Business, Universidad del Rosario, Bogotá, Colombia.
Adriana Rojas-VillarragaResearch Institute, Fundación Universitaria de Ciencias de la Salud - FUCS, Bogotá, Colombia.ORCID 0000-0003-3145-2440
Pedro Santos-MorenoScientific Direction, Biomab - Center for Rheumatoid Arthritis, Bogotá, Colombia.ORCID 0000-0001-7802-0317

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Rheumatoid arthritis (RA) affects approximately 0.3 to 1.2% of the world's population. The objective of this study was to identify the existing literature on economic evaluations of RA in Latin America. Patients and Methods: Studies of economic evaluations of patients with RA from 2000 to 2023 were analyzed using the databases PubMed, Scopus, Web of Science, Embase, Cochrane, and the Virtual Health Library following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Study quality was assessed using the Joanna Briggs Institute (JBI) tool, and qualitative analysis was done (following SwiM guidelines). Results: A total of 851 articles were identified. Following the application of inclusion criteria to titles and abstracts, 117 articles were initially considered eligible. Of these, 42 were excluded due to population or outcome-based errors, leaving 27 articles and 48 abstracts for analysis. Duplicates were removed prior to this process. The included studies involved various designs: cross-sectional, longitudinal, prospective, and retrospective. Brazil accounted for the highest proportion of publications (33.3%), followed by Colombia and Mexico, each contributing 26%. Most economic studies focused on cost analysis (86%), while cost-effectiveness studies and cost-utility studies represented 7.4% and 3.3%, respectively. Predominant perspectives included third-party payer 26%, insurers 14.8%, social providers 7.4%, and mixed providers 3.7%. In terms of publications of abstracts, Colombia leaded at 35.4%. The predominant perspective was that of the provider 66.6%, including the general perspective (37.5%), private (34.3%), public (22%), and mixed (6.2%) and the perspective of third-party payers (33.3%). Conclusion: Economic evaluations of rheumatoid arthritis in Latin America remain limited, with most studies focusing on cost analysis. Brazil, Colombia, and Mexico lead in publications, primarily from a provider perspective. Greater emphasis on cost-effectiveness and broader economic evaluations is needed to guide health policy in the region.

Indexed as

economic burdenLatin Americarheumatoid arthritis

Identifiers

PMID40260132
PMCPMC12011030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.