ArticleFrontiers in cardiovascular medicine2025
Associations between physical activity and cardiorespiratory fitness and adverse outcomes in patients with atrial fibrillation: a prospective cohort study.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Digital health solutions for chronic disease physical activity management: wearable devices, artificial intelligence, and public health implementation.Frontiers in public health · 2026Review
- Dose-dependent exercise promotes the transition from atrial protection to arrhythmogenic vulnerability: the intermediary role of calcium handling instability in substrate remodeling.Frontiers in physiology · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Background: Cardiorespiratory fitness (CRF) and physical activity (PA) are crucial for health and are gaining prominence in sports cardiology and rehabilitation medicine. This research study analyzes the impact of CRF and PA on the cardiovascular prognosis of patients with atrial fibrillation (AF), offering insights to optimize exercise interventions and enhance the scientific use of exercise in health. Methods: Cox regression models were used to assess the associations between CRF, PA, and endpoint events, including heart failure, stroke, myocardial infarction, and all-cause mortality. PA was categorized into four intensity levels, while CRF was quantified using three metrics: maximal oxygen uptake, (VO Results: Increased total physical activity [hazard ratio (HR) = 0.978; 95% confidence interval (CI): 0.961-0.995, Conclusion: This study shows that MPA significantly reduces cardiovascular risks in patients with AF, with all PA levels lowering mortality. Any PA level is beneficial, leading to immediate improvements, but excessive PA may yield diminishing returns or risks. Focusing solely on intensity or duration is insufficient; scientifically designed interventions, especially those boosting CRF (e.g., VO
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