Evidence map›Paper›PMID 40259887›Full record

ArticleEarly intervention in psychiatry2025

Enhancing Role Functioning in Clinical High Risk for Psychosis: An Open Trial of "InVEST" (Individualised Vocational and Educational Support and Training).

Michelle L West, Julia Pfluger, Shadi Sharif, Claire Goods, Michelle Friedman-Yakoobian

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michelle L WestDepartment of Psychiatry, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0003-1080-8452
Julia PflugerBeth Israel Deaconess Medical Center, Boston, Massachusetts, USA.ORCID https://orcid.org/0009-0008-0974-7924
Shadi SharifDepartment of Psychiatry, University of Colorado School of Medicine, Aurora, Colorado, USA.
Claire GoodsBeth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Michelle Friedman-YakoobianBeth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

Funding

InVEST: Individualized Vocational and Educational Support and Training for Clinical High Risk for Psychosis (CHR-P)R34MH122648 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FRIEDMAN-YAKOOBIAN, MICHELLE S, WEST, MICHELLE L. · 2021 to 2023
$573k
NIMH NIH HHS R34 5R34MH122648-02NIMH NIH HHS R34 MH122648
6 · The paper itself

Abstract

aimSchool and vocational ("role") functioning is an important treatment target for young people exhibiting signs of clinical high risk for psychosis (CHR-P). However, there are currently no evidence-based approaches to help people at CHR-P with role functioning difficulties.

methodThis manuscript describes the development and pilot open trial evaluation of "InVEST" (Individualised Vocational and Educational Support and Training). InVEST is a coaching program designed to enhance role functioning in youth at CHR-P. InVEST is designed to be flexible, low-intensity, and easy-to-train, and it is carried out by bachelor's and undergraduate-level "coaches" who work with clients individually for 4 months. The intervention specifically targets three mechanisms believed to relate to role functioning in this clinical population: (1) organisation, (2) task initiation, and (3) distress resilience. This manuscript describes a small open trial and the iterative development of a manual based on participant feedback about this intervention in preparation for a randomised controlled trial.

resultsAll participants (N = 5) completed the baseline assessment, 16 weeks of coaching, and follow-up, with no dropouts. Participants reported high satisfaction with the program, and participant feedback was used to iterate and develop the InVEST manual. Additionally, most participants showed improvement in role functioning (4/5), organisation and planning (4/5), and task initiation (3/5) following InVEST participation.

conclusionThis small pilot study provides initial support for the feasibility and acceptability of InVEST and suggests that further study in comparison to a control condition is warranted.

Indexed as

MentoringPsychotic DisordersVocational EducationAdolescentFemaleHumansMalePilot ProjectsYoung Adultclinical high riskcoachingeducational supportpsychosisrole functioning

Identifiers

PMID40259887
PMCPMC13286082

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.