Evidence map›Paper›PMID 40259762›Full record

ReviewThe Journal of infectious diseases2025

Immunoengineering: An Emerging Field in Infectious Diseases.

Alexander M Tatara, Antonios G Mikos, Dimitrios P Kontoyiannis

Abstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Innovation in antifungal therapy.EMBO molecular medicine · 2026
    Review
  2. The International Immunotherapy Society for Fungal Diseases.Antimicrobial agents and chemotherapy · 2026
    Article
  3. Review
  4. Immunotherapy for Infectious Diseases: Back to the Future.The Journal of infectious diseases · 2025
    Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Alexander M TataraDepartment of Biomedical Engineering, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-8579-4302
Antonios G MikosDepartment of Bioengineering, Rice University, Houston, Texas, USA.
Dimitrios P KontoyiannisDepartment of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-8051-2940

Funding

Biomaterials-based Immunoengineering for Periprosthetic Joint InfectionK08AI180362 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Alexander Mitchell Tatara · 2024 to 2026
$586k
MD Anderson Cancer Center CA16672National Institute of Allergy and Infectious Diseases R21/R33 AI12738NIAID NIH HHS K08 AI180362NIH HHSRobert C. Hickey Chair endowmentUniversity of Texas
6 · The paper itself

Abstract

As the disciplines of materials science, bioengineering, and immunology mature in the 21st century, the convergence science of immunoengineering has emerged as a paradigm to augment host immunity. By delivering biochemical and mechanical cues with engineered precision, the immune system can be stimulated to respond to specific antigens with a designed phenotype. While cancer has driven the early discoveries in immunoengineering, the field of infectious diseases stands to benefit tremendously by applying the concepts of immunoengineering to current clinical challenges. Antimicrobial resistance, highly communicable emerging pathogens, and infections in immunocompromised hosts are some examples of current problems that are suitable for immunoengineering approaches. Here, we will introduce basic concepts associated with immunoengineering and provide current examples applied to infectious diseases, including cell therapies, immunomodulating small molecule delivery, and next-generation vaccine development with implantable biomaterials.

Indexed as

BioengineeringCommunicable DiseasesAnimalsHumansVaccine Developmentchimeric antigen receptorimmunoengineeringimmunotherapyscaffoldvaccines

Identifiers

PMID40259762
PMCPMC12308683

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.