Evidence map›Paper›PMID 40259734›Full record

ReviewZoological research2025

Bromodomain-containing proteins in the unicellular eukaryote

Zhe Zhang, Ai-Li Ju, Yuan-Yuan Wang, Hong-Zhen Jiang, Yong-Qiang Liu, Shan Gao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Specific tracking of N-terminal clipping on histone H3 inMarine life science & technology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhe ZhangMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong 266003, China.
Ai-Li JuMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong 266003, China.
Yuan-Yuan WangMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong 266003, China.
Hong-Zhen JiangMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong 266003, China.
Yong-Qiang LiuMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong 266003, China.
Shan GaoMOE Key Laboratory of Evolution & Marine Biodiversity and Institute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao, Shandong 266003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bromodomain (BRD)-containing proteins are central mediators of gene regulation, serving as key components of chromatin remodeling complexes and histone recognition scaffolds. By specifically recognizing acetylated lysine residues on histones (Kac) via their conserved BRD, these proteins influence chromatin structure and gene expression. Although their overarching role is well-established, the precise molecular functions and mechanisms of individual BRD proteins remain incompletely characterized. The ciliate

Indexed as

Protozoan ProteinsTetrahymena thermophilaBromodomain Containing ProteinsGene Expression RegulationHistonesProtein DomainsBromodomain Containing ProteinsHistonesProtozoan ProteinsBromodomain-containing proteinsChromatin remodelingHistone acetylationTetrahymena

Identifiers

PMID40259734
PMCPMC12361904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.