Evidence map›Paper›PMID 40259699›Full record

ArticleBrain and behavior2025

A Computational Framework for Automated Puncture Trajectory Planning in Hemorrhagic Stroke Surgery.

Ziyue Ma, Feng Yan, Yongzhi Shan, Yaming Wang, Hong Wang

Abstract read
In one paragraph

Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ziyue MaDepartment of Neurosurgery, Capital Medical University Xuanwu Hospital, Beijing, China.
Feng YanDepartment of Neurosurgery, Capital Medical University Xuanwu Hospital, Beijing, China.
Yongzhi ShanDepartment of Neurosurgery, Capital Medical University Xuanwu Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-5510-1026
Yaming WangDepartment of Neurosurgery, Capital Medical University Xuanwu Hospital, Beijing, China.
Hong WangTianjin Key Laboratory of Neuromodulation and Neurorepair, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.ORCID https://orcid.org/0000-0002-1300-9595

Funding

Beijing Natural Science Foundation-Haidian Original Innovation Joint Fund Project L222022Chinese Academy of Medical Sciences Innovation Fund 2021-12M-1-058Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2023-PT310-05
6 · The paper itself

Abstract

backgroundThe treatment surgery for hemorrhagic stroke typically involves a puncture drainage procedure to remove the hematoma. However, the puncture targets for puncture and the puncture trajectory significantly influence the therapeutic outcome. This study proposes a computational framework integrating artificial intelligence (AI)-driven segmentation, principal component analysis (PCA), and empirical optimization to automate puncture path generation.

methodsA software platform named Puncture Trajectory ToolKits (PTK) was developed using C++/Python with ITK/VTK libraries. Key innovations include hybrid segmentation that combines ResNet-50 deep learning and adaptive thresholding for robust hematoma detection. PCA-based longest axis extraction was enhanced by Laplacian mesh smoothing. Skull quadrant theory and safety corridor modeling were used to avoid critical structures. Five complex clinical cases were used to validate the framework's performance.

resultsThe framework demonstrated high accuracy in puncture trajectory planning, with the optimized L2 path achieving a mean surgeon satisfaction score of 4.4/5 (Likert scale) compared to manual methods. The average angle difference between automatically generated and manually designed paths was 16.36°. These results highlight PTK's potential to enhance the efficiency and safety of robotic-assisted neurosurgery.

conclusionPTK establishes a systematic pipeline for trajectory planning assistance, demonstrating technical superiority over conventional methods. The high acceptance rate among surgeons and improved planning efficiency underscore its clinical applicability. Future integration with robotic systems and validation through clinical trials are warranted.

Indexed as

Hemorrhagic StrokeNeurosurgical ProceduresPuncturesSurgery, Computer-AssistedArtificial IntelligenceHumansPrincipal Component AnalysisSoftwarecomputational surgerydeep learninggeometric optimizationhemorrhagic strokepath planning

Identifiers

PMID40259699
PMCPMC12012241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.