Evidence map›Paper›PMID 40259615›Full record

ReviewBioscience reports2025

Toward safer and sustainable food preservation: a comprehensive review of bacteriocins in the food industry.

José Carlos Parada Fabián, Ana Karen Álvarez Contreras, Iván Natividad Bonifacio, Marcos Francisco Hernández Robles, Carlos Ramón Vázquez Quiñones, Elsa Irma Quiñones Ramírez, Carlos Vázquez Salinas

Abstract readReview
In one paragraph

Review in Bioscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Impact of Nisin on Growth Inhibition and Biofilm Formation Capacity ofInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Bacteriocin production byRSC advances · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Biotech (Basel (Switzerland)) · 2026
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Current research in food science · 2026
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

José Carlos Parada FabiánDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas-IPN, Santo Tomás, Manuel Carpio, Plutarco Elías Calles, Miguel Hidalgo, C.P. 11350 CDMX, Mexico city, Mexico.ORCID 0000-0003-4614-0693
Ana Karen Álvarez ContrerasDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas-IPN, Santo Tomás, Manuel Carpio, Plutarco Elías Calles, Miguel Hidalgo, C.P. 11350 CDMX, Mexico city, Mexico.ORCID 0000-0002-6443-038X
Iván Natividad BonifacioDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas-IPN, Santo Tomás, Manuel Carpio, Plutarco Elías Calles, Miguel Hidalgo, C.P. 11350 CDMX, Mexico city, Mexico.ORCID 0000-0002-2449-9278
Marcos Francisco Hernández RoblesDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas-IPN, Santo Tomás, Manuel Carpio, Plutarco Elías Calles, Miguel Hidalgo, C.P. 11350 CDMX, Mexico city, Mexico.ORCID 0000-0002-1079-3353
Carlos Ramón Vázquez QuiñonesDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas-IPN, Santo Tomás, Manuel Carpio, Plutarco Elías Calles, Miguel Hidalgo, C.P. 11350 CDMX, Mexico city, Mexico.ORCID 0000-0002-6803-1941
Elsa Irma Quiñones RamírezDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas-IPN, Santo Tomás, Manuel Carpio, Plutarco Elías Calles, Miguel Hidalgo, C.P. 11350 CDMX, Mexico city, Mexico.ORCID 0000-0003-0073-0655
Carlos Vázquez SalinasDepartamento de Biotecnología, Universidad Autónoma Metropolitana - Iztapalapa, San Rafael Atlixco 186, Leyes de Reforma 1A Sección, Iztapalapa, C.P. 09310 CDMX, Mexico City, Mexico.ORCID 0000-0002-9527-9926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriocins are considered promising natural biopreservatives in the food industry because of their broad spectrum of antimicrobial activity against Gram-positive bacteria and foodborne pathogens. This review provides information on several bacteriocins (nisin, pediocin, Micocin®, lacticin 3147, and enterocin AS-48), their mechanisms of action, applications, and discussion of regulatory requirements for their approval as food additives by the Food and Drug Administration (FDA) and the European Union to improve food safety. Nisin (the most studied bacteriocin), recognized as generally regarded as safe by the FDA, is used as a food preservative. Pediocin, derived from Pediococcus acidilactici, shows efficacy against Listeria species and is used in vegetable and meat products. Micocin®, a mixture of bacteriocins produced by Carnobacterium maltaromaticum CB1, is effective against Clostridium botulinum and Listeria monocytogenes. Lacticin 3147, composed of two peptides: Ltnα and Ltnβ, shows synergistic antibacterial activity with potential applications in the control of pathogens in dairy products. Enterococcin AS-48, produced by Enterococcus faecalis subsp. liquefaciens S-48, exhibits broad-spectrum antimicrobial activity against several Gram-positive bacteria and has been studied for biopreservation in a number of food products. For regulatory approval, the following criteria must be met: determination of identity, chemical composition, safety assessments, and recommended concentrations for use. Despite the difficulties posed by their large-scale production and purification, bacteriocins hold enormous potential for improving food safety and shelf life; however, further research is required to harness bacteriocins as future food preservation strategies.

Indexed as

BacteriocinsFood IndustryFood PreservationFood PreservativesAnti-Bacterial AgentsFood MicrobiologyFood SafetyHumansListeria monocytogenesAnti-Bacterial AgentsBacteriocinsFood Preservativesantimicrobial activitybacteriocinsbiopreservativescontrol of pathogensfood preservation

Identifiers

PMID40259615
PMCPMC12203937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.