Evidence map›Paper›PMID 40259609›Full record

SynthesisEuropean journal of neurology2025

Epilepsy and Employment in Europe: A Systematic Review of Literature.

F Narducci, G Lippa, G Baker, D Walsh, F Sofia, N Casalino, F Pigni, S Louissi, I Philipova, S Duttenhöfer and 6 more

Abstract readSystematic Review
In one paragraph

Synthesis in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

F NarducciResearch Unit of Neurology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.ORCID 0000-0002-6571-9054
G LippaOperative Research Unit of Neurology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
G BakerDepartment of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
D WalshInternational Bureau of Epilepsy (IBE), Dublin, Ireland.
F SofiaInternational Bureau of Epilepsy (IBE), Dublin, Ireland.
N CasalinoDepartment of Business and Management, Luiss Guido Carli University, Rome, Italy.
F PigniManagement and Technology, Grenoble Ecole de Management, Grenoble, France.
S LouissiManagement and Technology, Grenoble Ecole de Management, Grenoble, France.
I PhilipovaChamber of Commerce and Industry, Vratsa, Bulgaria.
S DuttenhöferEmcra GmbH, Berlin, Germany.
L RicciResearch Unit of Neurology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
B SancettaResearch Unit of Neurology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
J LanzoneNeurology Unit and Neurophysiology Service, IRCCS San Raffaele Scientific Institute, Milan, Italy.
M TombiniResearch Unit of Neurology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
V Di LazzaroResearch Unit of Neurology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
G AssenzaResearch Unit of Neurology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.ORCID 0000-0002-6160-4348

Funding

Erasmus+
6 · The paper itself

Abstract

backgroundEpilepsy is a chronic disorder affecting all aspects of individual life. People with epilepsy (PwE) reach seizure control in about 60% of cases. However, social integration issues are frequently overlooked. Unemployment and underemployment are markedly more common in PwE compared with the general population. With this review, we aimed to depict the current state of the employment situation in Europe with a focus on factors that may influence it.

methodsWe performed a systematic review on epilepsy and employment as part of EpilepsyPOWER Erasmus+ project (2021-1-IT02-KA220-ADU-000028349). Our search string was "Epilepsy AND Employment OR Job OR Work." Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines, we screened 7272 articles and selected 55 articles from 1958 to 2023. We extrapolated data on employment rate and status, also considering people with specific epileptic syndromes. We finally evaluated factors contributing to employment and unemployment.

resultsUnemployment rates range from similar to twice or three times the rates of the general population, depending on the countries and years examined. When analyzing factors contributing to employment conditions, most papers highlighted the importance of seizure control and employers' attitudes.

conclusionDeveloping specific legislation and programs to include PwE in the workplace could help their social integration. Moreover, seizure control seems to be the most relevant factor influencing the possibility of getting and maintaining a good job, demonstrating the importance of providing continuous follow-up and the best medical care to all PwE.

Indexed as

EmploymentEpilepsyUnemploymentEuropeHumansattitudesdisclosureemploymentepilepsyseizure severitystigmaunderemployment

Identifiers

PMID40259609
PMCPMC12011995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.