Evidence map›Paper›PMID 40259503›Full record

Trial reportJournal of the International Society of Sports Nutrition2025

Impact of carbohydrate timing on glucose metabolism and substrate oxidation following high-intensity evening aerobic exercise in athletes: a randomized controlled study.

Stig Mattsson, Fredrik Edin, Jonny Trinh, Peter Adolfsson, Johan Jendle, Stefan Pettersson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stig MattssonÖrebro University, School of Medicine and Health, Institute of Medical Sciences, Örebro, Sweden.ORCID 0000-0001-8444-1505
Fredrik EdinUniversity of Gothenburg, Department of Food and Nutrition, and Sport Science, Centre for Health and Performance, Gothenburg, Sweden.
Jonny TrinhUniversity of Gothenburg, Department of Food and Nutrition, and Sport Science, Centre for Health and Performance, Gothenburg, Sweden.
Peter AdolfssonÖrebro University, School of Medicine and Health, Institute of Medical Sciences, Örebro, Sweden.ORCID 0000-0001-7615-9737
Johan JendleÖrebro University, School of Medicine and Health, Institute of Medical Sciences, Örebro, Sweden.ORCID 0000-0003-1025-1682
Stefan PetterssonUniversity of Gothenburg, Department of Food and Nutrition, and Sport Science, Centre for Health and Performance, Gothenburg, Sweden.ORCID 0000-0003-4458-3343

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study aimed to investigate the impact of nutrient timing in relation to evening exercise. Specifically, it examined the effects of pre- or post-exercise carbohydrate (CHO) ingestion on glucose metabolism, glucose regulation, and overall substrate oxidation in well-trained athletes during and after physical exercise (PE), spanning the nocturnal period and the subsequent morning.

methodsTen male endurance cyclists participated in the study. The initial assessments included body composition measurements and an incremental cycle test to determine maximal oxygen uptake (

resultsPre-exercise CHO intake significantly lowered capillary glucose levels during steady-state exercise (mean difference 0.41 ± 0.27 mmol/L,

conclusionMorning glucose tolerance was markedly reduced in healthy athletes when CHO was ingested after evening exercise. However, the observed improvements in MetF during the OGTT compared to placebo post-exercise suggest a potential for enhanced athletic performance in subsequent exercise sessions. This opens exciting possibilities for future research to explore whether enhanced MetF induced by CHO-timing can translate to improved athletic performance, offering new avenues for optimizing training and performance.

Indexed as

Blood GlucoseDietary CarbohydratesExerciseGlucoseAdultAthletesBicyclingGlucose Tolerance TestHumansMaleOxidation-ReductionOxygen ConsumptionSports Nutritional Physiological PhenomenaTime FactorsYoung AdultBlood GlucoseDietary CarbohydratesGlucoseCarbohydrate metabolismcontinuous glucose monitoringexercisefat metabolismglucose tolerance testnutrition

Identifiers

PMID40259503
PMCPMC12016275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.