Evidence map›Paper›PMID 40259442›Full record

ArticleAlcohol, clinical & experimental research2025

Accelerated brain aging in alcohol users: Insights from machine learning.

Zhenhao Shi, Corinde E Wiers

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Accelerated brain aging in alcohol users: Insights from machine learning.Alcohol, clinical & experimental research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhenhao ShiDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-5697-2034
Corinde E WiersDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-2934-8794

Funding

Multivariate Modeling of the Neural Mechanisms of Treatment Response in Opioid AddictionK01DA051709 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI SHI, ZHENHAO · 2021 to 2025
$916k
Modulation of alcohol sensitivity and alcohol tolerance by exogenous ketones in humansR21AA031088 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI NANGA, RAVI PRAKASH REDDY, WIERS, CORINDE E · 2024 to 2025
$421k
Ketone supplementation as an intervention to alleviate alcohol withdrawal and improve brain energetics in Alcohol Use DisorderR21AA031337 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI NANGA, RAVI PRAKASH REDDY, WIERS, CORINDE E · 2024 to 2025
$376k
NIAAA NIH HHS AA031088NIAAA NIH HHS AA031337NIAAA NIH HHS R21 AA031088NIAAA NIH HHS R21 AA031337NIDA NIH HHS DA051709NIDA NIH HHS K01 DA051709
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40259442
PMCPMC12173762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.