Evidence map›Paper›PMID 40259390›Full record

ArticleJournal of biological engineering2025

Anti-inflammatory activity of magnetic fields emitted by graphene devices on cultured human cells.

Sara Franceschelli, Federica De Cecco, Stefano Benedetti, Valeria Panella, Lorenza Speranza, Alfredo Grilli, Pierdomenico D'Andrea

Abstract read
In one paragraph

Article in Journal of biological engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara FranceschelliDepartment of Medicine and Aging Sciences, University "G. d'Annunzio" Chieti- Pescara, Via dei Vestini 31, Chieti, 66100, Italy. sara.franceschelli@unich.it.
Federica De CeccoDepartment of Medicine and Aging Sciences, University "G. d'Annunzio" Chieti- Pescara, Via dei Vestini 31, Chieti, 66100, Italy.
Stefano BenedettiSchool of Medicine - University "G. d'Annunzio" Chieti- Pescara, Chieti, Italy.
Valeria PanellaDepartment of Medicine and Aging Sciences, University "G. d'Annunzio" Chieti- Pescara, Via dei Vestini 31, Chieti, 66100, Italy.
Lorenza SperanzaDepartment of Medicine and Aging Sciences, University "G. d'Annunzio" Chieti- Pescara, Via dei Vestini 31, Chieti, 66100, Italy.
Alfredo GrilliDepartment of Medicine and Aging Sciences, University "G. d'Annunzio" Chieti- Pescara, Via dei Vestini 31, Chieti, 66100, Italy. alfredo.grilli@unich.it.
Pierdomenico D'AndreaSchool of Medicine - University "G. d'Annunzio" Chieti- Pescara, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammation plays a key role in various diseases such as pancreatitis, cancer, and rheumatoid arthritis. Acute inflammation involves processes like vasodilation, increased vascular permeability, and leukocyte accumulation, which lead to cellular damage due to reactive oxygen species (ROS). Low-frequency electromagnetic fields (ELF-EMFs) have shown potential in reducing oxidative stress and inflammation. This study assesses the effectiveness of a new wearable device containing graphene quantum dots in reducing inflammation and oxidative stress in Jurkat T cells stimulated by lipopolysaccharide (LPS). The device is evaluated for its impact on ROS production and inflammation.

resultsThe results show that the device significantly lowers ROS levels and reduces the inflammatory response by decreasing pro-inflammatory cytokines such as IL-6, TNF-α, and IL-1β. Additionally, the device inhibits LPS-induced iNOS and COX-2 activity and modulates NF-κB signaling, indicating its potential as a therapeutic tool for managing inflammation and oxidative stress.

conclusionThese findings highlight the device's ability to combat inflammation, offering a non-invasive and effective approach for inflammatory diseases.

Indexed as

CytokinesGrapheneInflammationJurkat cellsLow-frequency electromagnetic fieldsPhoto-biomodulationQuantum Dot

Identifiers

PMID40259390
PMCPMC12013070

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.