Evidence map›Paper›PMID 40259387›Full record

ArticleWorld journal of surgical oncology2025

Pulmonary infection after esophageal cancer surgery: impact on the reality, risk factors and development of a predictive nomogram.

Junfeng Chen, Yan Zhao, Wanli Yang, Lili Duan, Liaoran Niu, Zhenshun Li, Yujie Zhang, Yan Miao, Aqiang Fan, Siyu Wei and 9 more

Abstract read
In one paragraph

Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Junfeng ChenDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Yan ZhaoDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Wanli YangDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Lili DuanDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Liaoran NiuDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Zhenshun LiDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Yujie ZhangDepartment of Histology and Embryology, School of Basic Medicine, Xi'an Medical University, Xi'an, 710021, China.
Yan MiaoDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Aqiang FanDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Siyu WeiDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Han BaiDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Yiding LiDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Xiaoqian WangDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Wei ZhouDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Qibin XieDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Chenyang WangDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Xi ChenDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China.
Yu HanDepartment of Otolaryngology, Xijing Hospital, Air Force Military Medical University, Xi'an, 710032, China. hyhlhj@126.com.
Liu HongDepartment of Digestive Surgery, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Xijing Hospital of Digestive Diseases, Air Force Military Medical University, Xi'an, 710032, China. hongliu180@126.com.

Funding

National Natural Science Foundation of China 82073210
6 · The paper itself

Abstract

backgroundAs a major complication after esophageal cancer (EC) surgery, postoperative pulmonary infection (PPI) is speculated to be associated with quality of life and survival after surgery. This study is aimed to explore the influence of PPI on the reality and establish a nomogram to predict PPI.

methodsData of patients undergoing esophagectomy was collected between January, 2016 and December, 2020 and divided into PPI and without PPI groups. Hospital costs and overall survival (OS) were compared between two groups. Univariate-multivariate analysis and LASSO-multivariate logistic regression were carried out to identify risk factors, and then two models were established based on them. To choose the better one, the receiver operating characteristic (ROC), the area under curve (AUC) and K-fold cross validation were compared between the models.

resultsThe incidence of PPI in 633 esophageal cancer patients was 30.2% (191/633). PPI caused a total economic burden of RMB11,872.31 yuan on each patient and a poorer overall survival (60.5% vs. 54.0%, P = 0.002). The final nomogram was established by Univariate-multivariate logistic regression, including four independent risk factors of BMI < 18 kg/m

conclusionIndividual prevention of PPI after esophagectomy would lead a lower financial burden and a better survival for EC patients.

Indexed as

Esophageal NeoplasmsEsophagectomyNomogramsPostoperative ComplicationsAgedFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPrognosisQuality of LifeRetrospective StudiesRisk FactorsROC CurveEconomic burdenEsophageal cancerPredictive modelPulmonary infectionRisk factorsSurvival analysis

Identifiers

PMID40259387
PMCPMC12013179

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.