ArticleActa epileptologica2025
Parenchymal neuro-sonological characteristics in epileptic patients and their correlation with cognitive dysfunction.
Article in Acta epileptologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic generalized epilepsies (IGEs) are the most common syndromes within the "genetic generalized epilepsies" (GGEs). Patients with IGE often exhibit cognitive comorbidities. The primary objective of this study is to investigate the correlation between brain parenchymal sonography characteristics and cognitive impairment in IGE.
methodsThis study enrolled 26 patients with IGE and 26 age- and sex-matched controls. All participants underwent comprehensive evaluations including clinical examination, electroencephalography, magnetic resonance imaging epilepsy protocol, transcranial sonography (TCS) for third and lateral ventricular diameter measurements, and cognitive assessment using the Addenbrooke's Cognitive Examination-III (ACE III).
resultsThis study found significantly lower scores in attention, memory, fluency, and total score of ACE-III in IGE patients compared to the control group (P-value = 0.011, 0.033, 0.007, and 0.001, respectively). However, no significant differences were observed between IGE patients and the control group in language and visuospatial score (P = 0.479 and 0.108, respectively). The average diameters of the third ventricle and lateral ventricle anterior horns were significantly larger in patients than in the control group (P-value 0.004, 0.009, and 0.012, respectively).
conclusionsIGE patients exhibit significant cognitive impairment and notable dilatation of the third ventricle and lateral ventricles horns, which may serve as markers of brain atrophy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.