Evidence map›Paper›PMID 40259348›Full record

ArticleJournal of medical case reports2025

Vaginal candidiasis attributed to hair, skin, and nails supplement: a case report.

Faith Whitlock, Akram Al-Makki, Brian Shepler

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Faith WhitlockPurdue University College of Pharmacy, West Lafayette, USA.
Akram Al-MakkiPurdue University College of Pharmacy, West Lafayette, USA.
Brian SheplerPurdue University College of Pharmacy, West Lafayette, USA. sheplerb@purdue.edu.ORCID http://orcid.org/0000-0001-5980-0692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis case report presents the first documented instance of vaginal candidiasis linked to the intake of a hair, skin, and nails supplement. CASE PRESENTATION: A 64-year-old Caucasian female patient, with a history of chronic kidney disease and multiple comorbidities, developed symptoms of vaginal yeast infection after beginning the supplement. The adverse event was evaluated using the Naranjo Adverse Drug Reaction Probability Scale, scoring a 5, indicating a probable association. Despite extensive literature searches, no similar cases were found, suggesting this might be a unique reaction. This report highlights potential safety concerns with dietary supplements, particularly those not regulated by the Food and Drug Administration, underscoring the need for further investigation into their adverse effects.

conclusionsThe case emphasizes the importance of considering dietary supplements as potential contributors to adverse health events, especially in patients with complex medical histories.

Indexed as

Candidiasis, VulvovaginalDietary SupplementsAntifungal AgentsFemaleHairHumansMiddle AgedNailsRenal Insufficiency, ChronicAntifungal AgentsAdverse drug eventSupplementsVaginal candidiasis

Identifiers

PMID40259348
PMCPMC12010589

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.