ArticleJournal of orthopaedic surgery and research2025
Modeling and construction of nomogram of cage subsidence after single-segment transforaminal lumbar interbody fusions.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Answer to the letter to the editor of A. Abudayeh, et al. concerning "Lateral lumbar interbody fusion with lateral plating: techniques, feasibility and efficacy" by T. Siu, et al. (Eur Spine J [2025]; doi:10.1007/s00586-025-09411-w).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
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7 authors.
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Abstract
objectiveThe purpose of this study is to explore and analyze the risk factors for interbody cage subsidence in patients undergoing single-segment transforaminal lumbar interbody fusion (TLIF) and to construct and validate a visual nomogram risk prediction model.
methodsA retrospective analysis was conducted on the clinical data of 159 patients who underwent single-segment TLIF at the Spine Surgery Department of Panyu District Traditional Chinese Medicine Hospital from January 2021 to June 2023. Using the caret package in R, patients were randomly divided into a training set (n = 111) and a validation set (n = 48) in a 7:3 ratio. Multivariable logistic regression was employed for variable selection and the construction of the nomogram model. The predictive model's discrimination, calibration, and clinical utility were evaluated using receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA).
resultsThere were no statistically significant differences in various indicators between the training set (n = 111) and the validation set (n = 48) (P > 0.05). Univariate analysis in the training set revealed that age, bone density, endplate morphology, anterior vertebral bone spurs, lumbar CT values, and VBQ were statistically significant. Multivariable logistic regression analysis indicated that bone density, anterior vertebral bone spurs, and lumbar CT values were independent predictors of interbody cage subsidence (P < 0.05), and a nomogram model was constructed based on these indicators. The area under the ROC curve (AUC) for the training set and validation set was 0.93 (95% CI 0.89-0.98) and 0.93 (95% CI 0.86-1.00), respectively. The calibration curves showed good fit (training set P = 0.616; validation set P = 0.904). DCA analysis demonstrated that the model has high clinical utility.
conclusionBone density, anterior vertebral bone spurs, and lumbar CT values are risk factors for interbody cage subsidence in patients after single-segment transforaminal lumbar interbody fusion. The constructed nomogram model exhibits good predictive value and clinical utility.
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