Evidence map›Paper›PMID 40259297›Full record

ArticleBMC musculoskeletal disorders2025

High posterior tibial slope increases anterior cruciate ligament elongation in unicompartmental knee arthroplasty during early-flexion of lunge.

Nan Zheng, Chunjie Xia, Huiyong Dai, Diyang Zou, Yubin Long, Zhiyong Hou, Qi Wang, Tsung-Yuan Tsai

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Nan ZhengSchool of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Chunjie XiaSchool of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Huiyong DaiDepartment of Orthopedics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Diyang ZouSchool of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China.
Yubin LongDepartment of Orthopaedics Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Zhiyong HouDepartment of Orthopaedics Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Qi WangDepartment of Orthopedics, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tsung-Yuan TsaiSchool of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, Shanghai, China. tytsai@sjtu.edu.cn.

Funding

National Natural Science Foundation of China 32371367Pudong New Area Science & Technology and Development Fund 210H1147900"Science and Technology Innovation Action Plan" of Science and Technology Commission of Shanghai Municipality 22S31906000, 23S31901000
6 · The paper itself

Abstract

backgroundIn-silico and in-vitro studies have revealed an appropriate posterior tibial slope (PTS) is critical for normal anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) tension and knee biomechanical behavior of unicompartmental knee arthroplasty (UKA). However, the effects of PTS on in-vivo elongation of ACL and PCL in UKA remains unknown. The study aimed to quantify in-vivo ACL and PCL elongations during lunge and analyze their relations with PTS.

methodsThirteen fixed-bearing (FB) and 11 mobile-bearing (MB) UKA patients were recruited. The postoperative medial PTS was defined as the angle between the tibial transverse plane (perpendicular to mechanical axis) and cut plane. Accurate knee spatial postures of UKA and contralateral native knees during single-leg lunge were measured by the dual fluoroscopic imaging system. The ACL (AM, PL bundles) and PCL (AL, PM bundles) footprints were determined based on anatomical features on femoral and tibial 3D surface model reconstructed from CT. A validated 3D wrapping method was used to measure ligament bundle length. The paired Wilcoxon signed-rank test was used to analyze the ligament elongation difference between bilateral knees. The Spearman correlation between PTS and average ligament elongation difference (ACL during 0-30° early-flexion, PCL during 60-100° deep-flexion) was calculated.

resultsThe elongation of FB UKA PCL double-bundle was larger than contralateral sides in most flexion range of lunge (Max-Difference: AL 7.6 ± 8.7%, PM 8.2 ± 5.1%, p < 0.05). In contrast, ACL double-bundle elongations of MB UKA in mid-flexion were larger than contralateral sides (Max-Difference: AM 8.0 ± 8.1%, PL 7.6 ± 9.8%, p < 0.05). The increased PTS was significantly relevant to the increased ACL double-bundle elongation difference of bilateral knees for both FB and MB UKA patients (R > 0.6, p < 0.05).

conclusionThere was abnormal in-vivo elongation of PCL in FB UKA and ACL in MB UKA during lunge and cause over-constraints to the contralateral knee. There was a positive correlation between PTS and ACL elongation difference for both FB and MB UKA, indicating excessive PTS should be avoided to preserve native ACL function in further UKA implantation. LEVELS OF EVIDENCE: III.

Indexed as

Anterior Cruciate LigamentArthroplasty, Replacement, KneeKnee JointPosterior Cruciate LigamentTibiaAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedRange of Motion, Articular2D-to-3D registrationCruciate ligamentFluoroscopyIn-vivo ligament elongationUnicompartmental knee arthroplasty

Identifiers

PMID40259297
PMCPMC12010665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.