Evidence map›Paper›PMID 40259233›Full record

ArticleBMC plant biology2025

Combined analysis of lncRNAs and mRNAs associated with coloration and wax formation during 'Fumei' Apple development.

Wenping Huo, Shasha Liu, Xiao Chen, Tingting Gu, Zhongkang Wang, Xiaolong Xu, Daliang Liu, Yugang Zhang, Shenghui Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenping Huo *College of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China.
Shasha Liu *College of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China.
Xiao Chen *College of Agronomy, Qingdao Agricultural University, Qingdao, Shandong, China.
Tingting GuCollege of Agricultural Sciences and Technology, Shandong Agriculture And Engineering University, Jinan, Shandong, China.
Zhongkang WangCollege of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China.
Xiaolong XuCollege of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China.
Daliang LiuCollege of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China.
Yugang ZhangCollege of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China. ygzhang@qau.edu.cn.
Shenghui JiangCollege of Horticulture, Engineering Laboratory of Genetic Improvement of Horticultural Crops of Shandong Province, Qingdao Agricultural University, Qingdao, Shandong, China. jsh2862317@163.com.

Funding

Agricultural Variety Improvement Project of Shandong Province 2023LZGCQY007China Agriculture Research System Foundation CARS-27National Natural Science Foundation of China 32102319Natural Science Foundation of Shandong Province ZR2021QC010Taishan Scholar Foundation of Shandong Province tstp20221134Talents of High-level Scientific Research Foundation of Qingdao Agricultural University 665/1121002Yantai Science and Technology Innovation Development Plan Strategic Research Project 2023ZLYJ116
6 · The paper itself

Abstract

'Fumei' apple is characterized by high anthocyanin content and thick wax layer. Long non-coding RNAs (lncRNAs) play essential roles in the growth and development of various plants via regulation of gene expression. This study explored the potential mechanism underlying anthocyanin accumulation and cuticular wax formation during the development of 'Fumei' apple fruit. The results demonstrated that anthocyanin accumulation correlates with fruit coloration, while wax content drives wax layer formation. A total of 6039 and 3410 differentially expressed genes (DEGs), as well as 230 and 131 differentially expressed lncRNAs (DELs) were identified in the M1/M2 and M2/M3 pairs, respectively, by using RNA-seq. In the M1/M2 pair, the DEGs were mainly enriched in the 'photosynthesis' and 'flavonoid biosynthesis' pathways; in the M2/M3 pair, the DEGs were significantly enriched in the 'photosynthesis' and 'cutin, suberine and wax biosynthesis' pathways. Furthermore, the structural and regulatory genes involved in anthocyanin and cuticular wax biosynthesis were investigated, and the potential lncRNAs and genes that may control the anthocyanin and cuticular wax biosynthesis were identified. This study provides candidate lncRNAs and potential regulatory genes associated with both the regulation of anthocyanins and wax during apple development.

Indexed as

MalusRNA, Long NoncodingRNA, MessengerRNA, PlantWaxesAnthocyaninsFruitGene Expression ProfilingGene Expression Regulation, PlantPigmentationAnthocyaninsRNA, Long NoncodingRNA, MessengerRNA, PlantWaxesAnthocyaninApplelncRNAsWax

Identifiers

PMID40259233
PMCPMC12010529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.