Evidence map›Paper›PMID 40259132›Full record

ArticleSleep & breathing = Schlaf & Atmung2025

Objective evaluation of major depressive disorder using sleep electroencephalography measured by an in-home portable one-channel device: a preliminary study.

Aoi Kawamura, Hiroshi Kadotani, Masahiro Suzuki, Makoto Uchiyama, Naoto Yamada, Kenichi Kuriyama

Abstract read
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aoi KawamuraDepartment of Psychiatry, Shiga University of Medical Science, Otsu, Japan.ORCID 0000-0002-7320-2848
Hiroshi KadotaniDepartment of Psychiatry, Shiga University of Medical Science, Otsu, Japan.
Masahiro SuzukiDepartment of Sleep-Wake Disorders, National Center of Neurology and Psychiatry, National Institute of Mental Health, Tokyo, Japan.
Makoto UchiyamaDepartment of Sleep-Wake Disorders, National Center of Neurology and Psychiatry, National Institute of Mental Health, Tokyo, Japan.
Naoto YamadaDepartment of Psychiatry, Shiga University of Medical Science, Otsu, Japan.
Kenichi KuriyamaDepartment of Psychiatry, Shiga University of Medical Science, Otsu, Japan. kenichik@ncnp.go.jp.ORCID 0000-0002-0254-4357

Funding

Japan Agency for Medical Research and Development 16hk0102041h0001Japan Agency for Medical Research and Development 23uk1024004h0003
6 · The paper itself

Abstract

purposeDecreased delta and increased alpha wave activity during sleep may be specific pathophysiological features of major depressive disorder; however, their usefulness as biomarkers remains unclear. We examined the use of mean alpha and delta wave power value indices during sleep to identify major depressive disorder using a portable electroencephalography device.

methodsWe compared the mean alpha and delta wave power value indices of six unmedicated patients with major depressive disorder and seven age- and sex-matched healthy controls using a portable electroencephalography device in this case-controlled study.

resultsThe ratio of the mean alpha power values for the non-rapid and rapid eye movement periods was significantly lower in the major depressive disorder group (1.3 ± 0.2) than in the healthy group (2.3 ± 0.6; P = 0.004). The ratio of the mean delta power values for the non-rapid eye movement and rapid eye movement periods did not differ between groups but negatively correlated significantly with the Hamilton Rating Scale for Depression score (r = -0.784, P = 0.002). The area under the receiver operating characteristic curve (95% confidence interval) of the mean alpha power ratio for non-rapid eye movement and rapid eye movement periods for distinguishing the two groups was 0.93 (0.78-1.00), and both sensitivity and specificity exceeded 85% at a cut-off value ≤ 1.71.

conclusionThe alpha- and delta-related power value indices may capture different aspects of major depressive disorder pathology.

Indexed as

ElectroencephalographyMajor Depressive DisorderPolysomnographyAdultAlpha RhythmCase-Control StudiesDelta RhythmFemaleHumansMaleMiddle AgedBiomarkerDepressionFast Fourier transformationIn-home examinationPolysomnographySleep EEG

Identifiers

PMID40259132
PMCPMC12011895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.