Evidence map›Paper›PMID 40259086›Full record

ArticleCommunications biology2025

SST neurons in the periaqueductal gray regulate urination and bladder function.

Junan Yan, Ziyan Gao, Xianping Li, Jun Li, Chunhui Yuan, Shanshan Liang, Jun Li, Guoxian Deng, Lingxuan Yin, Shutong Pang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Junan Yan *Center for Neurointelligence, School of Medicine, Chongqing University, Chongqing, China. junan_yan@aliyun.com.ORCID http://orcid.org/0000-0001-7704-5782
Ziyan Gao *Center for Neurointelligence, School of Medicine, Chongqing University, Chongqing, China.
Xianping Li *Department of Urology, PLA Naval Medical Center, Naval Medical University, Shanghai, China.
Jun LiSchool of Physical Science and Technology, Guangxi University, Nanning, China.ORCID http://orcid.org/0009-0000-7883-3174
Chunhui YuanDepartment of Urology, PLA Naval Medical Center, Naval Medical University, Shanghai, China.
Shanshan LiangBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.ORCID http://orcid.org/0000-0003-2179-7824
Jun LiBrain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University, Chongqing, China.
Guoxian DengDepartment of Urology, PLA Naval Medical Center, Naval Medical University, Shanghai, China.
Lingxuan YinGuangxi Key Laboratory of Special Biomedicine and Advanced Institute for Brain and Intelligence, School of Medicine, Guangxi University, Nanning, China.
Shutong PangGuangxi Key Laboratory of Special Biomedicine and Advanced Institute for Brain and Intelligence, School of Medicine, Guangxi University, Nanning, China.
Wei ShaoGuangxi Key Laboratory of Special Biomedicine and Advanced Institute for Brain and Intelligence, School of Medicine, Guangxi University, Nanning, China.ORCID http://orcid.org/0000-0001-6299-0239
Xiaowen XiaDepartment of Urology, PLA Naval Medical Center, Naval Medical University, Shanghai, China.
He ZhuDepartment of Clinical Research Institute, Central People's Hospital of Zhanjiang, Guangdong Medical University, Zhanjiang, China. 63393022@qq.com.ORCID http://orcid.org/0000-0001-5107-7575
Jiwei YaoCenter for Neurointelligence, School of Medicine, Chongqing University, Chongqing, China. jiwei_yao89@126.com.ORCID http://orcid.org/0009-0003-5063-6584

Funding

China Postdoctoral Science Foundation 2021M700602National Natural Science Foundation of China (National Science Foundation of China) 31970946National Natural Science Foundation of China (National Science Foundation of China) 32100912
6 · The paper itself

Abstract

Urination, a fundamental physiological process, is intricately regulated by central neural circuits. The periaqueductal gray (PAG) is a critical hub for urination control, yet the specific neuronal subtypes involved remain undefined. Here, we identified somatostatin (SST)-expressing neurons in the lateral and ventrolateral PAG (l/vlPAG) as key regulators of urination. SST

Indexed as

NeuronsPeriaqueductal GraySomatostatinUrinary BladderUrinationAnimalsFemaleMaleMiceOptogeneticsSomatostatin

Identifiers

PMID40259086
PMCPMC12012073

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.