Evidence map›Paper›PMID 40259036›Full record

SynthesisBiogerontology2025

Dietary inflammatory index (DII) and telomere length: a systematic review.

Joice da Silva Castro, Carolynne Martins Teixeira, Daniela Mayumi Usuda Prado Rocha, Andréia Queiroz Ribeiro, Ana Claudia Pelissari Kravchychyn, Helen Hermana Miranda Hermsdorff

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Biogerontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joice da Silva Castro *Group for Studies and Practices in Aging, Department of Nutrition and Health, Nutrition and Health (GREENS), Universidade Federal de Viçosa, Viçosa, Minas Gerais, 36570-000, Brazil.ORCID 0000-0001-5640-5937
Carolynne Martins Teixeira *Laboratory of Clinical Analysis and Genomics, Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Av. PH Rolfs, S/N, Viçosa, Minas Gerais, 36570-000, Brazil.ORCID 0000-0002-8418-5051
Daniela Mayumi Usuda Prado RochaLaboratory of Clinical Analysis and Genomics, Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Av. PH Rolfs, S/N, Viçosa, Minas Gerais, 36570-000, Brazil.ORCID 0000-0001-6130-0179
Andréia Queiroz RibeiroGroup for Studies and Practices in Aging, Department of Nutrition and Health, Nutrition and Health (GREENS), Universidade Federal de Viçosa, Viçosa, Minas Gerais, 36570-000, Brazil.ORCID 0000-0001-6546-1252
Ana Claudia Pelissari KravchychynLaboratory of Clinical Analysis and Genomics, Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Av. PH Rolfs, S/N, Viçosa, Minas Gerais, 36570-000, Brazil.ORCID 0000-0002-2919-2806
Helen Hermana Miranda HermsdorffLaboratory of Clinical Analysis and Genomics, Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Av. PH Rolfs, S/N, Viçosa, Minas Gerais, 36570-000, Brazil. helenhermana@ufv.br.ORCID 0000-0002-4441-6572

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior , Brasil 001
6 · The paper itself

Abstract

Dietary intake influences inflammation and may impact telomere length (TL), a biomarker of biological aging. However, the relationship between the inflammatory potential of the diet and TL remains unclear. This review systematically assessed whether higher Dietary Inflammatory Index (DII) scores, indicative of pro-inflammatory diets, are associated with shorter TL. Searches in PubMed, Embase, Scopus, Web of Science, and Cochrane up to October 2024 identified nine eligible studies, involving 123,923 participants (53% women), aged 9-80 years. Seven studies were cross-sectional, and two were longitudinal, with follow-ups of 5-10 years. Most studies (n = 4) examined adult and older adult populations of both sexes. DII values ranged from -6.48 (anti-inflammatory) to 3.98 (pro-inflammatory). None included all DII parameters, and three adjusted for energy intake. Four studies linked higher DII to shorter TL, focusing on European adults with and without cardiovascular risk, healthy American adults, and Chinese older adults with mild cognitive impairment. This systematic review presents limited data to provide a definitive conclusion on the association between higher DII and shorter TL. Additional studies that address the limitations identified in this review are needed.

Indexed as

AgingDietInflammationTelomereTelomere HomeostasisTelomere ShorteningAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedAgingDiet qualityFood intakeInflammationTelomere

Identifiers

PMID40259036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.