ArticleScientific reports2025
Identification of atopic dermatitis-associated diseases based on the National health and nutrition examination survey (NHANES) 2013-2018.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Combined effect of atopic dermatitis and chronic kidney disease on overall and cardiovascular disease mortality.Scientific reports · 2026Article
- Advances in Bioprinting to Model Immune-Mediated Skin Diseases.Advanced healthcare materials · 2026Review
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12 authors.
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Abstract
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Massive cohort studies revealed that AD was associated with allergic diseases, inflammatory diseases, autoimmune diseases, cardiovascular diseases, and mental disorders. We comprehensively and systematically analyzed the correlation between AD and diseases to identify AD-associated diseases (ADADs). We involved 17,924 individuals from the National Health and Nutrition Examination Survey (NHANES) (2013-2018) dataset, and analyzed the correlation between AD and 422 diseases classified by International Classification of Diseases-10 (ICD-10) using four logistic regression models. We found that AD is significantly associated with 33 diseases: (1) allergic diseases, including urticaria, allergic rhinitis, allergy, asthma, other seasonal allergic rhinitis; (2) inflammatory diseases, including noninfective gastroenteritis and colitis, acute atopic conjunctivitis, osteoarthritis, and unspecified chronic bronchitis; (3) mental disorders with impairment (MDI), including comorbid mental disorders, schizophrenia and sleep disorder; (4) malignant tumors, including malignant neoplasm of prostate, malignant (primary) neoplasm and malignant neoplasm of breast; (5) other symptoms and diseases, other symptoms and diseases, such as wheezing, pruritus and gout. Notably, non-infective gastroenteritis and colitis showed the strongest correlation (OR: 38.39, 95% CI: 3.08-478.01) among the 33 ADADs. We identified 33 ADADs based on the NHANES (2013-2018) dataset, which provide new insights into understanding the development of these ADADs associated with AD.
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