Evidence map›Paper›PMID 40258953›Full record

ArticlePediatric radiology2025

Using deep learning for estimation of time-since-injury in pediatric accidental fractures.

Farah W Brink, Brent Adler, Sven Bambach, Charmaine B Lo, Steven Rust, Christopher W Bartlett, Logan Bradshaw, M Katherine Henry, Diana Messer

Abstract read
In one paragraph

Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Farah W BrinkNationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. farah.brink@nationwidechildrens.org.
Brent AdlerAbigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, USA.
Sven BambachAbigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, USA.
Charmaine B LoNationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Steven RustAbigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, USA.
Christopher W BartlettNationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
Logan BradshawNationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
M Katherine HenryClinical Futures, Division of General Pediatrics, and Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, USA.
Diana MesserUniversity of Tennessee Health Science Center, Memphis, USA.

Funding

AHRQ HHS K08 HS028847AHRQ HHS K08HS028847CDC HHS 1R49CE003074-01Nationwide Children’s HospitalNCIPC CDC HHS R49 CE003074
6 · The paper itself

Abstract

backgroundEstimating time-since-injury of healing fractures is imprecise, encompassing excessively wide timeframes. Most injured children are evaluated at non-children's hospitals, yet pediatric radiologists can disagree with up to one in six skeletal imaging interpretations from referring community hospitals. There is a need to improve image interpretation by considering additional methods for fracture dating.

objectiveTo train and validate deep learning models to correctly estimate the age of pediatric accidental long bone fractures. MATERIALS AND

methodsThis secondary data analysis used radiographic images of accidental long bone fractures in children <6 years at the time of injury seen at a large Midwestern children's hospital between 2000-2016. We built deep learning models both to classify fracture images into different age groups and to directly estimate fracture age (time-since-injury). We used cross-validation to evaluate model performance across various metrics, including confusion matrices, sensitivity/specificity, and activation maps for age classification, and mean absolute error (MAE) and root mean squared error (RMSE) for age estimation.

resultsOur study cohort contained 2,328 radiographs from 399 patients. Overall, our models performed above baselines for fracture age classification and estimation, both when trained/validated across all bones and on specific bone types. The best model was able to estimate fracture age for any long bone with a MAE of 6.2 days and with 68% of estimates falling within 7 days of the correct fracture age.

conclusionOur study successfully demonstrated that, for radiographic dating of accidental fractures of long bones, deep learning models can estimate time-since-injury with above-baseline accuracy.

Indexed as

Accidental InjuriesDeep LearningFractures, BoneImage Processing, Computer-AssistedRadiographic Image Interpretation, Computer-AssistedChildChild, PreschoolClavicleFeasibility StudiesHumansInfantRadiographySoftware ValidationTime FactorsArtificial intelligenceBoneChildrenDatingDeep learningFracturesRadiographs

Identifiers

PMID40258953
PMCPMC12306432

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.