ArticleScientific reports2025
A streamlined POCT solution for rapid infectious disease detection.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Recent advances in MXene-molecularly imprinted polymer hybrid nanocomposites for electrochemical detection of pandemic-related biomarkers.Analytical and bioanalytical chemistry · 2026Review
- Technological innovations and breakthrough pathways in syphilis diagnosis: addressing global resurgence and the journey toward elimination.Frontiers in cellular and infection microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Point-of-care testing (POCT) plays a crucial role in infectious disease screening due to its rapid detection and portability. However, current POCT systems face challenges such as lengthy sample preparation time, complex nucleic acid extraction, and limited real-time data transmission, extending patient waiting time. This study presents iPonatic, an integrated POCT system with a quantitative dropper for efficient sample addition, a low-cost cartridge utilizing one-step rapid nucleic acid release technology, and real-time data synchronization via a cloud platform. Patients can receive test reports within 30 min. The system was validated for both respiratory and sexually transmitted pathogens, showing consistent [Formula: see text] values with standard quantitative PCR. Clinical validation on 1159 samples demonstrated an AUC above 0.98 for all targets, with sensitivity exceeding 95% and specificity reaching 100%. iPonatic is ideal for primary healthcare, epidemic response, and resource-limited settings. It offers an efficient solution to enhance diagnostics and reduce patient waiting time, supporting timely responses to public health needs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.