Evidence map›Paper›PMID 40258857›Full record

ArticleScientific reports2025

Molecular characterization of suburothelial fibrosis in murine acute recurrent bladder inflammation.

Ji Yeon Lee, Jiha Kim, Tong Zhou, Justin P Malogan, Sang Don Koh, Brian A Perrino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ji Yeon LeeDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, 89557, USA.
Jiha KimDepartment of Neurosurgery, Kangwon National University College of Medicine, Chuncheon-Si, Gangwon-Do, 24289, Korea.
Tong ZhouDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, 89557, USA.
Justin P MaloganDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, 89557, USA.
Sang Don KohDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, 89557, USA.
Brian A PerrinoDepartment of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, 89557, USA. bperrino@med.unr.edu.

Funding

Molecular and Functional Mechanisms of Purinergic Relaxation in Detrusor MuscleR01DK098388 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KOH, SANG DON · 2013 to 2017
$1.6M
NIDDK NIH HHS R01 DK098388
6 · The paper itself

Abstract

Chronic fibrosis replaces functional organ tissue with scar tissue by overproduction of a thick and stiff extracellular matrix. Bladder fibrosis decreases bladder compliance, ultimately resulting in overactive bladder. The phenoconversion of fibroblasts into myofibroblasts is the defining feature of fibrosis. Recently, regionally distinct populations of bladder platelet-derived growth factor receptor alpha positive (PDGFRα

Indexed as

CystitisUrinary BladderAnimalsDisease Models, AnimalFemaleFibroblastsFibrosisInflammationMiceMice, Inbred C57BLMyofibroblastsReceptor, Platelet-Derived Growth Factor alphaSignal TransductionReceptor, Platelet-Derived Growth Factor alphaBladder inflammationCyclophosphamideFibroblastMyofibroblastPDGFRα+ cellsUrinary bladder

Identifiers

PMID40258857
PMCPMC12012138

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.