Evidence map›Paper›PMID 40258594›Full record

ArticleJournal of the American Chemical Society2025

Stereoselective Total Synthesis of Nimbolide.

David B Ryffel, Peter C Ryffel, Matteo Martinelli, Vineet R Pillai, David Sarlah

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A General Approach toJournal of the American Chemical Society · 2026
    Article
  2. Stereodivergent Construction ofJournal of the American Chemical Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David B RyffelDepartment of Chemistry, Rice University, Houston, Texas 77005, United States.ORCID 0000-0001-7094-9826
Peter C RyffelDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Matteo MartinelliDepartment of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Vineet R PillaiDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
David SarlahDepartment of Chemistry, Rice University, Houston, Texas 77005, United States.ORCID 0000-0002-8736-8953

Funding

Synthesis of Biologically Active TerpenoidsR01GM144489 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI David Sarlah · 2023 to 2026
$1.4M
NIGMS NIH HHS R01 GM144489
6 · The paper itself

Abstract

A stereoselective total synthesis of nimbolide has been achieved in a convergent, 11-step sequence from α-methyl-(

Identifiers

PMID40258594
PMCPMC12768561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.