Evidence map›Paper›PMID 40257946›Full record

Observational studyBiomedica : revista del Instituto Nacional de Salud2025

Savings to the Colombian health system with the implementation of externally funded oncology clinical trials

Sandra Aruachan Vesga, Manuel González, Danis M Rojas, Javier Ospina, Santiago Duque-Varela, Andrés Ángel Castaño

Abstract readObservational StudyEnglish Abstract
In one paragraph

Observational study in Biomedica : revista del Instituto Nacional de Salud, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra Aruachan VesgaUnidad de Estudios Clínicos, Clínica IMAT Oncomédica Auna, Montería, Colombia.ORCID 0000-0003-4002-1423
Manuel GonzálezServicio de Oncología Clínica, Clínica IMAT Oncomédica Auna, Montería, Colombia.ORCID 0000-0001-7468-2700
Danis M RojasUnidad de Estudios Clínicos, Clínica IMAT Oncomédica Auna, Montería, Colombia.ORCID 0009-0005-7088-9014
Javier OspinaUnidad de Estudios Clínicos, Clínica IMAT Oncomédica Auna, Montería, Colombia.ORCID 0000-0002-4626-1316
Santiago Duque-VarelaÁrea de Estrategia de Modelos de Aseguramiento, Access Co S.A.S., Pereira, Colombia.ORCID 0009-0009-0988-6905
Andrés Ángel CastañoÁrea de Estrategia de Modelos de Aseguramiento, Access Co S.A.S., Pereira, Colombia.ORCID 0009-0005-3839-2438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. Spending on drugs to treat cancer will increase by 9-12% annually until 2025. For health systems in high and middle-income countries –such as Colombia– and with an increasing trend of new cancer cases, clinical research can contribute to the efficient use of the system resources available without undermining the timeliness and quality of healthcare. Objective. To calculate the savings generated to the Colombian health system by the implementation of externally funded clinical trials for cancer. Materials and methods. We conducted an observational, longitudinal, descriptive, and retrospective study analyzing participant’s medical records of clinical trials between 2016 and 2022 at the Clínica IMAT Oncomédica Auna, Colombia. Results. The total savings to the health system for external financing of oncology drugs was USD $1,526,320, and the monthly weighted average savings per patient was USD $3,257. The participation of breast cancer patients in randomized controlled clinical trials (n = 138) accounted for 24% (USD $369,363) of the total savings. Participants with clinical stage IV and III accounted for 41.7% (USD $636,475) and 31.06% (USD $473,159), respectively, of the total savings to the general social security health system in Colombia from external financing of oncological drugs. Conclusion. The participation of cancer patients in clinical trials mitigated costs to the Colombian health system, especially in women with breast cancer and in those patients with clinical stage IV of the disease.

Indexed as

Antineoplastic AgentsCost SavingsDelivery of Health CareMedical OncologyNeoplasmsColombiaDrug CostsFemaleHumansLongitudinal StudiesRandomized Controlled Trials as TopicRetrospective StudiesAntineoplastic Agentsclinical trialcost savingsdrug industryhealth systemsneoplasms

Identifiers

PMID40257946
PMCPMC12147872

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.