Evidence map›Paper›PMID 40257850›Full record

ArticleBiopsychosocial science and medicine2025

Child Maltreatment and Whole-person Health: Investigation of Psychosocial Buffers Using Structural Equation Modeling.

Yanping Jiang, Emily A Brinck, Sarah Ascienzo, Angela Groves, Kathy Trang, Charlotte V Farewell

Abstract read
In one paragraph

Article in Biopsychosocial science and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily A Brinck
Sarah Ascienzo
Angela Groves
Kathy Trang
Charlotte V Farewell

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
ZDV &3TC NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFECTED INFANTS &M01RR000865 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASHINGTON, ARNOLD E. · 1985 to 2011
$43.4M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
WIHS INTENSIVE PHARMACOKINETIC STUDY (IPS)M01RR023942 · NCRR · GEORGETOWN UNIVERSITY · PI FEDEROFF, HOWARD J. · 2007 to 2009
$6.9M
Summer Training Program in Integrative Methods for Mental and Physical HealthR25MH136652 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Briana Mezuk · 2024 to 2026
$441k
NCATS NIH HHS UL1 TR002373NCRR NIH HHS M01 RR000865NCRR NIH HHS M01 RR023942NCRR NIH HHS UL1 RR025011NIA NIH HHS P01 AG020166NIMH NIH HHS R25 MH136652
6 · The paper itself

Abstract

objectiveThe purpose of this study was to investigate psychosocial factors that may modify associations between child maltreatment and whole-person health (ie, depressive symptoms, chronic health conditions, psychological well-being, and inflammation).

methodsData were drawn from a subsample ( N = 1255) of Midlife in the United States study, a national longitudinal study of health and well-being. Structural equation modeling was applied to test hypotheses.

resultsChild maltreatment was associated with more depressive symptoms (standardized β = 0.29, p < .001), more chronic health conditions ( β = 0.24, p < .001), poorer psychological well-being ( β = -0.25, p < .001), and elevated C-reactive protein (β = 0.06, p = .041), but not with interleukin-6 (IL-6; β = 0.06, p = .055). There were significant interaction effects between child maltreatment and psychological resources on depressive symptoms (unstandardized b = -0.009, SE = 0.005, p = .045) and IL-6 ( b = -0.001, SE = 0.000, p = .042). Specifically, there were stronger relationships between child maltreatment and more depressive symptoms and elevated IL-6 at low levels of psychological resources than at high levels of psychological resources. There were no statistically significant interaction effects between child maltreatment and social resources on any health outcomes.

conclusionsHigh levels of psychological resources significantly mitigate the long-term effects of child maltreatment on depressive symptoms and inflammation among middle-aged and older adults.

Indexed as

Adult Survivors of Child AbuseChild AbuseDepressionAdultAgedChildChronic DiseaseC-Reactive ProteinFemaleHumansInflammationInterleukin-6Latent Class AnalysisLongitudinal StudiesMaleMiddle AgedC-Reactive ProteinInterleukin-6biopsychosocial modelchild maltreatmentinflammationpsychological resourcessocial resourceswhole person health

Identifiers

PMID40257850
PMCPMC12677245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.