Evidence map›Paper›PMID 40257608›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Development of

Ji Tao, Rui Cao, Zhe Lei, Xiao Wang, Renli Luo, Yuanyuan Zhou, Yanlin Li, Xiaoping Xu, Xiaosheng Liu, Chunrong Qu and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ji TaoHuman Phenome Institute, Fudan University, Shanghai, China.
Rui CaoDepartment of Nuclear Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhe LeiDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China.
Xiao WangDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China.
Renli LuoState Key Laboratory of Drug Research, Molecular Imaging Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Yuanyuan ZhouState Key Laboratory of Drug Research, Molecular Imaging Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Yanlin LiHuman Phenome Institute, Fudan University, Shanghai, China.
Xiaoping XuDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China.
Xiaosheng LiuDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China.
Chunrong QuState Key Laboratory of Drug Research, Molecular Imaging Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Shaoli SongDepartment of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, China. shaolisong@163.com.
Mei TianHuman Phenome Institute, Fudan University, Shanghai, China. tianmei@fudan.edu.cn.
Zhen ChengState Key Laboratory of Drug Research, Molecular Imaging Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. zcheng@simm.ac.cn.ORCID 0000-0001-8177-9463

Funding

Gansu Science and Technology Major Project 23ZDFA014National Natural Science Foundation of China U2267221Natural Science Foundation of Shanghai 24ZR1477300Ningbo Major Research and Development Plan Project 2024Z214Shandong Laboratory Program SYS202205Shanghai Municipal Science and Technology Major Project 2023SHZDZX02State Key Laboratory of Drug Research SIMM0120231004
6 · The paper itself

Abstract

purposeMelanoma is a highly aggressive skin cancer with poor prognosis, highlighting the need for early detection. This study aims to develop a

methodsSix potential

resultsThese six probes exhibited high radiolabeling yields (> 95%) and radiochemical purities (> 95%). In vitro cell uptake and blocking experiments demonstrated their binding capability and specificity for melanin. Among these probes,

conclusion

Indexed as

MelaninsMelanomaSingle Photon Emission Computed Tomography Computed TomographyTechnetiumTomography, Emission-Computed, Single-PhotonAnimalsCell Line, TumorHumansMiceTissue DistributionMelaninsTechnetium99mTechnetiumImaging probeMelaninMelanomaSPECT

Identifiers

PMID40257608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.