Evidence map›Paper›PMID 40257565›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Single-cell Epigenomic Profiling with High-throughput Droplet scChIP-seq.

Justine Marsolier, Eve Moutaux, Kevin Grosselin, Andrew Griffiths, Céline Vallot

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justine MarsolierCNRS UMR3244, Institut Curie, PSL University, Paris, France.
Eve MoutauxCNRS UMR3244, Institut Curie, PSL University, Paris, France.
Kevin GrosselinLaboratoire de Biochimie, ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
Andrew GriffithsLaboratoire de Biochimie, ESPCI Paris, PSL Research University, CNRS UMR8231 Chimie Biologie Innovation, Paris, France.
Céline VallotCNRS UMR3244, Institut Curie, PSL University, Paris, France. Celine.Vallot@curie.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our high-throughput scChIP-seq approach combines droplet microfluidics with single-cell DNA barcoding to study the heterogeneity of epigenomes (H3K27me3, H3K4me3, H3K27Ac, H3K4me1) in a cellular population of several thousand cells with a coverage of up to 10,000 unique loci per cell.

Indexed as

Epigenesis, GeneticEpigenomicsHigh-Throughput Nucleotide SequencingSingle-Cell AnalysisHistonesHumansMicrofluidicsHistonesChromatinDNA barcodingDroplet microfluidicsEpigenome profilingHistone modifications

Identifiers

PMID40257565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.