ArticleCellular and molecular life sciences : CMLS2025
Organoids in disease modeling and regenerative medicine.
Article in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Injectable microsphere-based delivery strategies for stem cells and their derivatives in tissue regeneration.Bioactive materials · 2026Review
- Immunoids: Building immunocompetent organoids from human pluripotent stem cells.Cell stem cell · 2026Review
- Endodermal Organoids Along Two Axes: Single-Organ Fidelity, Inter-Organ Reconstruction, and the Unbuilt Gut-Lung Frontier.Stem cell reviews and reports · 2026Review
- Engineering the Healing Process: Advanced In Vitro Wound Models and Technologies.Biomedicines · 2026Review
- Organoids: technology refining, current applications and future directions.Molecular biomedicine · 2026Review
- The research advances of crosstalk between cancer-associated fibroblasts and tumor cells using co-culture organoids.Cell death & disease · 2026Review
- Technological Innovations and the Translational Path of Kidney Organoids.Biomedicines · 2026Review
- Development of ovine hepatic organoids: a powerfulFrontiers in veterinary science · 2026Article
- Development of a High-Throughput Screening Platform and a Pathogenesis Model forInternational journal of molecular sciences · 2025Article
- Application and challenges of tumor organoid technology in precision immunotherapy.Frontiers in immunology · 2025Review
- Dual-Function Biomaterials for Postoperative Osteosarcoma: Tumor Suppression and Bone Regeneration.Research (Washington, D.C.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Organoid technology has the potential to revolutionize biomedical research by providing more physiologically relevant models for studying human development, disease mechanisms, and therapeutic development. Derived from stem cells, organoids self-organize into three-dimensional tissues that replicate the structures and functions of their in vivo counterparts. Their ability to mimic organ-specific microstructures offers new tools for investigating organogenesis, modeling genetic disorders, and screening potential therapeutics using human cells. Additionally, organoids hold promise for regenerative medicine as potential transplantable tissues for repairing or replacing damaged organs. However, challenges such as batch variability, standardization, vascularization, long-term viability, and lack of immune cells remain, hindering their clinical translation and use in disease studies. Recent efforts have focused on improving reproducibility, incorporating bioengineering techniques for enhanced maturation, and optimizing differentiation methods. This collection highlights recent advances in the respiratory, renal, and retinal organoid systems. From refining cryopreservation methods to using organoid models for virus neutralization and inflammatory studies, these contributions emphasize the potential of organoids in translational research and regenerative medicine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.