Evidence map›Paper›PMID 40257245›Full record

ArticleACS biomaterials science & engineering2025

Self-Powered Oxygen Microbubble Generator for Decontamination of Anaerobic Biofilm-Fouled Bioimplants.

Eun-Hyuk Lee, Hyunsub Kim, Joo Hun Lee, Youngjoon Kim, Ho-Beom Kwon, Young-Jun Lim, Hyunjoon Kong, Sang-Woo Lee, Myung-Joo Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. ROS-responsive HBioactive materials · 2027
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eun-Hyuk LeeDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Hyunsub KimDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Joo Hun LeeDepartments of Chemical and Biomolecular Engineering, Scott H. Fisher Multi-Cellular Engineered Living System Theme, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Youngjoon KimDepartment of Physiology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, South Korea.ORCID 0009-0008-0339-6430
Ho-Beom KwonDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Young-Jun LimDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.
Hyunjoon KongDepartments of Chemical and Biomolecular Engineering, Scott H. Fisher Multi-Cellular Engineered Living System Theme, Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-4680-2968
Sang-Woo LeeDepartment of Physiology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 03080, South Korea.ORCID 0000-0003-3950-6722
Myung-Joo KimDepartment of Prosthodontics, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 110-749, South Korea.ORCID 0000-0003-2020-5284

Funding

Self-Locomotive Antimicrobial Micro-Robot (SLAM) Enhancing Biofilm-Infected Wound HealingR01AI160671 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2022 to 2025
$1.7M
NIAID NIH HHS R01 AI160671
6 · The paper itself

Abstract

Biomedical devices often feature a microgap: confined, minuscule spaces that foster bacterial infiltration and biofilm formation. For instance, peri-implantitis with prevalence rates of 4.7-45% at the patient level is a major complication driven by biofilm infections, characterized by chronic inflammation and implant failure. Anaerobic biofilm residing within the microgap serves as a major source of the peri-implantitis, but tools that remove the biofilm are lacking. Therefore, this study presents a novel preventive strategy employing

Indexed as

BiofilmsDecontaminationDental ImplantsMicrobubblesOxygenPorphyromonas gingivalisHumansHydrogen PeroxideManganese CompoundsOxidesPeri-ImplantitisDental ImplantsHydrogen PeroxideManganese Compoundsmanganese dioxideOxidesOxygenbiofilmsdecontaminationdental implantsdiatomsmanganese oxidemicrogapnanozyme

Identifiers

PMID40257245
PMCPMC12076271

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.