Evidence map›Paper›PMID 40257134›Full record

ArticleThe Indian journal of medical research2025

Fracture risk prediction & kidney function at different stages of chronic kidney disease: A correlation study.

Karana Ram, Nipin Kalal, Rajesh Jhorawat, Ravindra Shukla, Arpit Agarwal, P Gangadevi

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Article in The Indian journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Karana RamCollege of Nursing, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Nipin KalalCollege of Nursing, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Rajesh JhorawatDepartment of Nephrology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Ravindra ShuklaDepartment of Endocrinology and Metabolism, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Arpit AgarwalDepartment of Nephrology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
P GangadeviCollege of Nursing, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

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6 · The paper itself

Abstract

Background & objectives Mineral bone disease commonly occurs in individuals with chronic kidney disease (CKD) and increases fracture risk due to deficiency in bone quality and quantity. The FRAX score attempts to estimate fracture risk better. The primary aim of this study was to evaluate the prediction and correlation of fracture risk with different stages of CKD. Methods This was a correlational study. Data were collected from 95 individuals at different stages of CKD using non-probability consecutive sampling. The clinical and laboratory parameters were compared with the FRAX score in all CKD patients. Results A total of 95 CKD patients with a mean age of 51.42±9.95 yr were selected. Of these, 66.3 per cent between 40-55 yr, 25.3 per cent were 56-70 yr, and 8.4 per cent were ≥70 yr. There were 62 (65.3%) males and 33 (34.7%) females, and more than half (60%) were from rural areas. Age (P<0.001), occupation (P<0.005), and area of residence (P<0.003) showed a significant association with the FRAX score for major osteoporotic fracture risk. The FRAX score for predicting hip fracture risk showed a significant association with factors such as age, occupation, and area of residence, with P values of <0.001, 0.003, and 0.031, respectively. Additionally, the FRAX score for assessing the risk of major osteoporotic fractures demonstrated a significant association with various stages of CKD (P=0.018). Similarly, for hip fracture, there was a significant increase in the risk between stage III and V CKD patients (P=0.038). Interpretation & conclusions Based on the study findings it was found that the FRAX score was significantly associated with different stages of CKD, both for major osteoporotic as well as hip fracture risk.

Indexed as

Hip FracturesOsteoporotic FracturesRenal Insufficiency, ChronicAdultAgedBone DensityFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsBone mineral densitychronic kidney diseaseDEXA scanfracture riskFRAX score

Identifiers

PMID40257134
PMCPMC12010776

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