Evidence map›Paper›PMID 40257011›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Detection and differentiation of undiagnosed dementia in the emergency department: A pilot referral pathway.

Cameron Gettel, James Galske, Katy Araujo, Scott Dresden, Jeffrey Dussetschleger, Lynne Iannone, James Lai, Pamela Martin, Bridget Mignosa, Kayla Muschong and 3 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
  6. Detection and differentiation of undiagnosed dementia in the emergency department: A pilot referral pathway.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cameron GettelDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
James GalskeUniversity of Connecticut School of Medicine, Farmington, Connecticut, USA.
Katy AraujoSection of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Scott DresdenDepartment of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Jeffrey DussetschlegerSection of Digestive Disease, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Lynne IannoneSection of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
James LaiDivision of Geriatrics and Palliative Care, Department of Internal Medicine, NYU Grossman School of Medicine, New York, New York, USA.
Pamela MartinDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Bridget MignosaDepartment of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Kayla MuschongDepartment of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Basmah SafdarDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Sandra WeintraubDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Ula HwangDepartments of Emergency Medicine and Population Health, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-3715-3073

Funding

Training Core (I)U54AG063546 · NIA · BROWN UNIVERSITY · PI Abraham Aizer Brody, SUSAN L MITCHELL · 2019 to 2026
$125.9M
Development and validation of the Patient-Reported Outcome Measure - Older adult care Transitions from the Emergency Department (PROM-OTED) toolR03AG073988 · NIA · YALE UNIVERSITY · PI GETTEL, CAMERON · 2021 to 2022
$335k
Alzheimer's Association ARCOM-22-878456CDC HHS 75D30121F0002National Institute of Health (NIH)NIA AD/ADRD Health Care Systems Research Collaboratory (IMPACT Collaboratory) U54AG063546NIA NIH HHS R03 AG073988NIA NIH HHS R03AG073988NIA NIH HHS U54 AG063546
6 · The paper itself

Abstract

introductionCognitive impairment (CI) is under-recognized by emergency department (ED) clinicians, and processes for cognitive screening and outpatient referrals are limited.

methodsThis pilot study tested the feasibility of ED clinicians referring older adult patients identified through CI screening and direct clinician referral for outpatient cognitive evaluation. Telephone interviews and chart reviews were conducted on 100 patients about their emergency care, cognitive function, and referral status.

resultsA total of 9359 ED patients were screened for memory and thinking problems, with 650 (6.9%) reporting such issues. A total of 100 patients were discharged and referred for outpatient cognitive evaluation, consisting of 37 referred from screening and 67 through direct clinician referral. Of these, 26 (26.0%) scheduled and 19 (19.0%) completed outpatient evaluations within 100 days. Fifteen (78.9%) were formally diagnosed with dementia, CI, or memory loss. DISCUSSION: ED clinicians are able to identify and appropriately refer older patients with CI for outpatient evaluation. Future studies can improve referral rates with solutions addressing detection and follow-up challenges. HIGHLIGHTS: Screening for cognitive impairment and outpatient referral for cognitive evaluation is feasible in the emergency department. Nearly 80% of patients who completed follow-up were diagnosed with cognitive impairment, including probable dementia and Alzheimer's disease. Significant gaps and barriers remain in maintaining outpatient follow-up from initial referral from the emergency department, with less than one in five patients completing outpatient evaluations.

Indexed as

DementiaEmergency Service, HospitalReferral and ConsultationAgedAged, 80 and overCognitive DysfunctionFeasibility StudiesFemaleHumansMaleMiddle AgedNeuropsychological TestsPilot Projectscognitive impairmentdementiaearly detectionemergency departmentpilot studyscreening

Identifiers

PMID40257011
PMCPMC12010273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.