Evidence map›Paper›PMID 40256832›Full record

ArticleMovement disorders clinical practice2025

Lewy Body Dementia Research in Latin America: A Scoping Review.

Carlos Cano-Gutiérrez, Salomón Salazar-Londoño, Felipe Botero-Rodriguez, Salomón Páez-García, Salomón Giraldo, José Manuel Santacruz-Escudero, Dag Aarsland, Miguel Germán Borda, COL‐DLB

Abstract readScoping Review
In one paragraph

Article in Movement disorders clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Shining a Spotlight on Dementia with Lewy Bodies in Latin America.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carlos Cano-GutiérrezIntellectus Memory and Cognition Center, Hospital Universitario San Ignacio, Bogotá, Colombia.ORCID https://orcid.org/0000-0001-5680-7880
Salomón Salazar-LondoñoSemillero de Neurociencias y Envejecimiento, Ageing Institute, Medical School, Pontificia Universidad Javeriana, Bogotá, Colombia.ORCID https://orcid.org/0000-0002-9302-3601
Felipe Botero-RodriguezIntellectus Memory and Cognition Center, Hospital Universitario San Ignacio, Bogotá, Colombia.ORCID https://orcid.org/0000-0003-1537-5211
Salomón Páez-GarcíaSemillero de Neurociencias y Envejecimiento, Ageing Institute, Medical School, Pontificia Universidad Javeriana, Bogotá, Colombia.ORCID https://orcid.org/0009-0005-9488-8868
Salomón GiraldoSemillero de Neurociencias y Envejecimiento, Ageing Institute, Medical School, Pontificia Universidad Javeriana, Bogotá, Colombia.ORCID https://orcid.org/0009-0001-9931-0863
José Manuel Santacruz-EscuderoIntellectus Memory and Cognition Center, Hospital Universitario San Ignacio, Bogotá, Colombia.ORCID https://orcid.org/0000-0001-5051-3056
Dag AarslandCentre for Age-Related Medicine (SESAM), Stavanger University Hospital, Stavanger, Norway.ORCID https://orcid.org/0000-0001-6314-216X
Miguel Germán BordaCentre for Age-Related Medicine (SESAM), Stavanger University Hospital, Stavanger, Norway.ORCID https://orcid.org/0000-0001-5832-0603
COL‐DLB

Funding

Helse VestNasjonalforeningen for FolkehelsenNational Institute for Health and Care ResearchSouth London and Maudsley NHS Foundation Trust
6 · The paper itself

Abstract

backgroundDementia research in Latin America (LA) has primarily focused on Alzheimer's Disease and Frontotemporal Dementia, while Lewy body dementia (LBD) has been largely forgotten.

objectiveWe aimed to review the available evidence on LBD in LA, offering a comprehensive perspective for understanding the lack of reports and the unique challenges and characteristics of this region.

methodsWe carried out a scoping review in databases: PubMed, EMBASE, LILACS, and Web of Science. Original studies that included participants with LBD were analyzed.

resultsOf the 1388 studies identified, 70 met the inclusion criteria for this review. Among them, 63 were cross-sectional studies, three were cohort studies, two followed a case-control methodology, and only two were non-randomized clinical trials. These studies primarily examined clinical manifestations, risk factors, neuropsychiatric and non-motor symptoms, as well as cognitive impairment and its assessment in LBD within LA. Regarding geographical distribution, 52 studies were conducted in Brazil, seven in Argentina, the rest in Peru, Mexico, Colombia, Cuba, and Chile.

conclusionsLBD research in LA is underrepresented, with most studies being cross-sectional, few utilizing a longitudinal design, and only two clinical trials, both of which lack rigorous methodology. Challenges include weak study designs, high heterogeneity, limited trials, and unclear differentiation within the LBD spectrum. Addressing these gaps requires increasing awareness, strengthening research capacity, securing funding, and fostering international collaboration.

Indexed as

Biomedical ResearchLewy Body DiseaseCross-Sectional StudiesHumansLatin AmericadementiaLatin AmericaLewy body diseasereviewsynucleinopathies

Identifiers

PMID40256832
PMCPMC12371463

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.