Evidence map›Paper›PMID 40256797›Full record

ArticleChemPlusChem2025

Low-Energy Electron-Induced Dissociation of the Radiosensitizing Agent Sanazole.

Farhad Izadi, Masoomeh Mahmoodi-Darian, Thomas F M Luxford, Jaroslav Kočišek, Stephan Denifl, Milan Ončák

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemPlusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farhad IzadiInstitut für Ionenphysik und Angewandte Physik, Universität Innsbruck, Technikerstraße 25, 6020, Innsbruck, Austria.
Masoomeh Mahmoodi-DarianInstitut für Ionenphysik und Angewandte Physik, Universität Innsbruck, Technikerstraße 25, 6020, Innsbruck, Austria.
Thomas F M LuxfordDepartment of Dynamics of Molecules and Clusters, J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, v.v.i., Dolejškova 3, 18223, Prague, Czech Republic.
Jaroslav KočišekDepartment of Dynamics of Molecules and Clusters, J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, v.v.i., Dolejškova 3, 18223, Prague, Czech Republic.ORCID 0000-0002-6071-2144
Stephan DeniflInstitut für Ionenphysik und Angewandte Physik, Universität Innsbruck, Technikerstraße 25, 6020, Innsbruck, Austria.ORCID 0000-0001-6072-2070
Milan OnčákInstitut für Ionenphysik und Angewandte Physik, Universität Innsbruck, Technikerstraße 25, 6020, Innsbruck, Austria.ORCID 0000-0002-4801-3068

Funding

Austrian Science Fund 10.55776/I5390Austrian Science Fund 10.55776/P30332Programme Johannes Amos Comenius CZ.02.01.01/00/22_008/0004558 "AMULET"
6 · The paper itself

Abstract

Sanazole is a hypoxic radiosensitizer for which the activation mechanism in cells has been suggested to involve initial reduction. Herein, electron attachment to sanazole under isolated conditions and upon microhydrations is investigated. Employing mass spectrometry supported by quantum chemical calculations, the anion formation mechanism and subsequent fragmentation pathways are examined. In the case of electron attachment to the isolated molecule, predominantly dissociative electron attachment is observed. The most prominent fragment anion, (NTR-yl)

Indexed as

ElectronsRadiation-Sensitizing AgentsTriazolesMass SpectrometryRadiation-Sensitizing AgentsTriazoleselectron attachmentelectron‐induced dissociationradiosensitizersanazol

Identifiers

PMID40256797
PMCPMC12261046

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.