Evidence map›Paper›PMID 40256756›Full record

ArticleCrystal growth & design2025

Developing a Vial-Scale Methodology for the Measurement of Nucleation Kinetics Using Evaporative Crystallization: A Case Study with Sodium Chloride.

Michele Chen, Leif-Thore Deck, Luca Bosetti, Marco Mazzotti

Abstract read
In one paragraph

Article in Crystal growth & design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michele ChenInstitute of Energy and Process Engineering, ETH Zürich, 8092 Zürich, Switzerland.ORCID https://orcid.org/0000-0003-3441-2225
Leif-Thore DeckInstitute of Energy and Process Engineering, ETH Zürich, 8092 Zürich, Switzerland.ORCID https://orcid.org/0000-0002-0955-6801
Luca BosettiInstitute of Energy and Process Engineering, ETH Zürich, 8092 Zürich, Switzerland.ORCID https://orcid.org/0000-0001-6657-6510
Marco MazzottiInstitute of Energy and Process Engineering, ETH Zürich, 8092 Zürich, Switzerland.ORCID https://orcid.org/0000-0002-4948-6705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding nucleation kinetics is vital for designing crystallization processes, yet traditional measurement methods based on cooling are unsuitable for compounds with temperature-independent solubility. This study introduces an experimental procedure to measure the nucleation kinetics based on evaporative crystallization and applies it to sodium chloride (NaCl) in water. By systematically varying the experimental conditions such as temperature and evaporation gas flow rate, we obtained a comprehensive data set for the nucleation of NaCl crystals that allowed estimating kinetic parameters using a rate expression derived from classical nucleation theory (CNT). This work demonstrates the robustness of evaporation as a method for measuring the nucleation kinetics that is applicable regardless of how the solubility of a compound depends on the temperature.

Identifiers

PMID40256756
PMCPMC12006966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.