Evidence map›Paper›PMID 40256747›Full record

ArticleClinical case reports2025

Age-Related Long-Term Longitudinal Changes in Left Ventricular Mechanical Function in Breast Cancer Patients Undergoing Anthracycline and Trastuzumab Treatment.

Begimai Akbalaeva, Priti Singh, Salman Khan

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Begimai AkbalaevaDepartment of Clinical Disciplines 1, International Medical Faculty Osh State University Osh Kyrgyzstan.
Priti SinghDepartment of Premedical Sciences, and Nutritional, Biochemical and Molecular Sciences American University School of Medicine Aruba Oranjestad Aruba.
Salman KhanDepartment of Pathological Processes and Therapeutics American University School of Medicine Aruba Oranjestad Aruba.ORCID https://orcid.org/0000-0001-8003-6983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age significantly influences the severity of chemotherapy-induced cardiotoxicity (cardiotoxicity) in HER2-positive breast cancer patients. Comprehensive cardiac monitoring before, during, and after anthracycline and trastuzumab regimens is essential. Tailored assessments can help identify vulnerable patients, optimize treatment, and mitigate risks of heart complications while maintaining therapy efficacy.

Indexed as

anthracyclinebreast cancercardiotoxicitychemotherapyspeckle‐tracking echocardiographytrastuzumab

Identifiers

PMID40256747
PMCPMC12008165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.