Evidence map›Paper›PMID 40256695›Full record

ArticleJournal of conservative dentistry and endodontics2025

Dentinal tubule penetration of a silicone-based endodontic sealer following N-acetyl cysteine intracanal medicament removal using ultrasonic agitation and laser activated irrigation - An

Pranjali S Narvekar, Sunita Shivanand, Sneha Patil, Sarvesh Raikar, Amrita Mallick, Preeti K Doddwad

Abstract read
In one paragraph

Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pranjali S NarvekarDepartment of Conservative Dentistry and Endodontics, KLE Academy of Higher Education and Research, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
Sunita ShivanandDepartment of Conservative Dentistry and Endodontics, KLE Academy of Higher Education and Research, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
Sneha PatilDepartment of Conservative Dentistry and Endodontics, KLE Academy of Higher Education and Research, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
Sarvesh RaikarDepartment of Conservative Dentistry and Endodontics, KLE Academy of Higher Education and Research, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
Amrita MallickDepartment of Conservative Dentistry and Endodontics, KLE Academy of Higher Education and Research, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.
Preeti K DoddwadDepartment of Conservative Dentistry and Endodontics, KLE Academy of Higher Education and Research, KLE VK Institute of Dental Sciences, Belagavi, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: The removal of intracanal medicament is essential for sealer penetration and the success of endodontic therapy. Aims: To evaluate and compare the dentinal tubule penetration of a silicone-based endodontic sealer following N-acetyl cysteine (NAC) intracanal medicament removal using ultrasonic agitation and laser-activated irrigation. Materials and Methods: Eighty-one extracted single-rooted mandibular premolars were decoronated and prepared with ProTaper Universal rotary files up to MAF F3. To prepare medicament, NAC powder was mixed with propylene glycol in the ratio of 1:1, placed using a size #30 Lentulospiral, and specimens stored in an incubator for 14 days. The specimens were then instrumented with #30 Hedström and divided into three groups according to final irrigant activation techniques: Group I: Diode laser activation, Group II: Passive Ultrasonic agitation, Group III: No agitation (positive control). Canals were obturated with GuttaFlow bioseal sealer mixed with 0.1% Rhodamine B dye and gutta-percha cones and incubated for 7 days. The specimens were sectioned horizontally to obtain 1 mm thick sections from 2, 5, and 8 mm from the apex. Sections were examined under Confocal Laser Scanning Microscope to measure the depth of sealer penetration (in µm). Statistical Analysis: One-way analysis of variance and Tukeys multiple Results: The highest mean depth of penetration of 728.52 µm was seen with Group I, followed by Group II and least was seen in Group III. Conclusions: Diode laser activation group was most effective in the removal of NAC intracanal medicament from all the three regions of the root canal.

Indexed as

Confocal laser scanning microscopeconventional syringe needle irrigationdiode laser activationguttaFlow biosealN-acetyl cysteinepassive ultrasonic agitation

Identifiers

PMID40256695
PMCPMC12007743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.