ArticleJournal of conservative dentistry and endodontics2025
Evaluating the effectiveness of various disinfectants in deep carious lesions: An
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
5 authors.
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Abstract
Aims: The study aimed to assess and compare the cavity disinfection efficacy of 2% chlorhexidine, 940 nm diode laser, and photodynamic therapy (PDT) with Rose Bengal-functionalized chitosan nanoparticles (CS-NPs) in deep carious lesions. Settings and Design: This randomized controlled, parallel clinical trial was conducted in the Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Ahmedabad. A simple randomization technique was used for randomization of samples. A total of 90 patients participated in this study. Subjects and Methods: Ninety participants with reversible pulpitis were randomly assigned to three groups, each receiving a different cavity disinfectant: 2% chlorhexidine, 940 nm diode laser, and PDT with Rose Bengal-functionalized CS-NPs. Dentinal samples were collected before and after cavity disinfection, and microbiological analysis for total viable count (TVC), Statistical Analysis Used: Statistical analysis involved the Wilcoxon signed-rank, Kruskal-Wallis, and Tukey's tests. Results: Intragroup comparison showed high significant reductions in TVC, Conclusions: All three cavity disinfectants significantly reduced total vital count,
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