Evidence map›Paper›PMID 40256566›Full record

ArticleACS omega2025

Self-Tuning Reaction Conditioning of a Paper-Based Electrochemical Biosensor for Acetaldehyde Detection.

Shaimah Rinda Sari, Harune Sakaguchi, Kenji Shida, Masato Tominaga

Erratum issuedAbstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Shaimah Rinda SariFaculty of Science and Engineering, Saga University, 1 Honjomachi, Saga 840-8502, Japan.ORCID https://orcid.org/0000-0001-9289-8804
Harune SakaguchiGraduate School of Science and Engineering, Saga University, 1 Honjomachi, Saga 840-8502, Japan.
Kenji ShidaFaculty of Engineering, Kumamoto University, Kumamoto 860-8555, Japan.
Masato TominagaFaculty of Science and Engineering, Saga University, 1 Honjomachi, Saga 840-8502, Japan.ORCID https://orcid.org/0000-0002-1103-7576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a self-tuning reaction conditioning strategy for a paper-based electrochemical biosensor for identifying acetaldehyde. In this study, a three-electrode system was integrated onto paper that had already been cut into shape where the working electrode was modified by the incorporation of aldehyde dehydrogenases (ALDHs). A high concentration of acetate buffer embedded inside the electrode allowed ideal conditions where every measurement taken always results in the same optimum pH. The conditioned paper-based electrode demonstrated a rapid response within ∼20-30 s and a similar linear response at lower and higher acetaldehyde concentrations at pH 4 and 8. Because of our novel electrode preparation strategy, each measurement resulted in the same optimal conditions for enzyme activity ensuring precise and sensitive evaluation of acetaldehyde.

Identifiers

PMID40256566
PMCPMC12004139

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.