Evidence map›Paper›PMID 40256486›Full record

ArticleGland surgery2025

Prevalence of Hashimoto's thyroiditis in papillary thyroid cancer and its association with aggressive characteristics.

Zi-Fang Xu, Huan Ge, Neng Tang, Zi-En Qin, Hai-Long Tan

Abstract read
In one paragraph

Article in Gland surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zi-Fang Xu *Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0009-0004-8080-2210
Huan Ge *Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0003-0434-0822
Neng TangDepartment of General Surgery, Xiangya Hospital, Central South University, Changsha, China.
Zi-En Qin *Department of Thyroid and Breast Surgery, Lixian People's Hospital, Changde, China.ORCID https://orcid.org/0000-0001-9697-2119
Hai-Long Tan *Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-3345-5277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hashimoto's thyroiditis (HT) has been associated with papillary thyroid cancer (PTC), yet whether the clinicopathological features of PTC are affected by HT remains unknown. The purpose of this study was to investigate the association of HT with clinicopathological features of PTC. Methods: We conducted a multicenter cross-sectional study to retrospectively evaluate the association of HT with clinicopathological features of PTC in the central provinces of China. The association between HT with clinicopathological features of PTC (including pathological HT and clinical HT) was evaluated by logistic regression analysis. Results: A total of 15,305 patients with PTC were enrolled to this study, with a median age of 42 years at diagnosis, including 11,465 women (74.9%) and 3,840 men (25.1%). The overall prevalence of HT in PTC patients was 22.9% (3,505/15,305). Compared with PTC patients without HT, pathological HT was a potential protective factor for several aggressive characteristics of PTC, including Conclusions: PTC patients often have concomitant HT. Some potential links between the 2 entities are present. Pathological HT is a potential protective factor for some aggressive characteristics of PTC, whereas this effect does not present in clinical HT, which has guiding significance for clinical treatment decision-making.

Indexed as

AggressiveHashimoto’s thyroiditis (HT)papillary thyroid cancer (PTC)prevalence

Identifiers

PMID40256486
PMCPMC12004320

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.