Evidence map›Paper›PMID 40256333›Full record

ArticleFrontiers in reproductive health2025

Community PrEP delivery for adolescent girls and young women: insights from the DREAMS PrEP Choice Study in Johannesburg, South Africa.

Nicolette Prea Naidoo, Nqaba Mthimkulu, Ngcwalisa Jama, Glory Chidumwa, Brison Chabalala, Tafadza Mhakakora, Lauren Parmley, Saiqa Mullick

Abstract read
In one paragraph

Article in Frontiers in reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Lenacapavir for HIV Prevention in Africa: Opportunities, Barriers, and Policy Priorities.Journal of the International Association of Providers of AIDS Care
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicolette Prea NaidooWits RHI, University of Witwatersrand, Johannesburg, South Africa.
Nqaba MthimkuluWits RHI, University of Witwatersrand, Johannesburg, South Africa.
Ngcwalisa JamaWits RHI, University of Witwatersrand, Johannesburg, South Africa.
Glory ChidumwaWits RHI, University of Witwatersrand, Johannesburg, South Africa.
Brison ChabalalaWits RHI, University of Witwatersrand, Johannesburg, South Africa.
Tafadza MhakakoraWits RHI, University of Witwatersrand, Johannesburg, South Africa.
Lauren ParmleyUnited States Agency for International Development (USAID), Pretoria, South Africa.
Saiqa MullickWits RHI, University of Witwatersrand, Johannesburg, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Long-acting pre-exposure prophylaxis (PrEP) methods have the potential to significantly reduce HIV acquisition and increase the uptake and effective use of PrEP among adolescent girls and young women (AGYW). We describe the implementation approach for delivering the PrEP ring and outline provider perspectives related to community-based service delivery. Methods: The DREAMS PrEP Choice Study, a mixed-methods implementation science study delivering PrEP choice to women 18 years and older, was conducted in Johannesburg, South Africa. We extracted quantitative enrollment data from the routine patient management system (REDCap) and collected qualitative data from four focus group discussions with providers. Quantitative data are presented descriptively whilst qualitative data were analyzed using content and thematic analyses. Results: Between October 2023 and April 2024, 657 participants were enrolled and offered PrEP choice. Most (72.1%, Conclusion: As one of the first studies to implement community-based services for PrEP choice, the early results indicate the feasibility of delivering this service with moderate uptake of PrEP by AGYW. Understanding the service delivery conditions required to offer informed choice is important for supporting national scale-up.

Indexed as

AGYWcommunity-basedHIV preventionPrEPSouth Africa

Identifiers

PMID40256333
PMCPMC12006157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.