Evidence map›Paper›PMID 40256293›Full record

ReviewCurrent urology2024

A simplified treatment algorithm for chronic scrotal content pain syndrome.

Sergey Kravchick, Sijo J Parekattil, Gennady Bratslavsky, Matthew R Beamer, Robert Moldwin, Daniel Shulman, J Curtis Nickel

Abstract readReview
In one paragraph

Review in Current urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sergey KravchickArthur Smith Institute for Urology of the Northwell Health System, Riverhead, NY, USA.
Sijo J ParekattilAvant Concierge Urology, Winter Garden, FL, USA.
Gennady BratslavskyDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY, USA.
Matthew R BeamerDepartment of Urology, SUNY Upstate Medical University, Syracuse, NY, USA.
Robert MoldwinArthur Smith Institute for Urology of the Northwell Health System, Lake Success, NY, USA.
Daniel ShulmanBinghamton University, Binghamton, NY, USA.
J Curtis NickelDepartment of Urology, Queen's University, Kingston, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic scrotal content pain (CSCP) is a devastating condition characterized by localized scrotal pain that persists for ≥ 3 months and interferes with daily activities. Approximately 2.5% of all urology outpatient visits are associated with CSCP. General urologists may have difficulty treating these patients because of uncertainties regarding the etiology and pathophysiology of CSCP. Therefore, we aimed to provide a simplified diagnostic and treatment approach for CSCP by subdividing it into distinct categories. Materials and methods: We systematically reviewed the published literature in the PubMed, MEDLINE, and Cochrane databases for all reports on CSCP diagnosis and treatment using the keywords "chronic scrotal content pain," "testicular pain," "orchialgia," "testicular pain syndrome," "microdenervation of the spermatic cord," "post-vasectomy pain syndrome," "post-inguinal hernia repair pain," "testialgia," and "pudendal neuralgia." This review included only CSCP-related articles published in English language. Results: We subdivided CSCP syndrome into 5 clinical presentation types, including hyperactive cremasteric reflex, pain localized in the testicles, pain in the testis, spermatic cord, and groin, pain localized in the testicles, spermatic cord, groin, and pubis, and pain in the testicles, spermatic cord/groin, and penis/pelvis. Treatments were adjusted stepwise for each type and section. We included more information regarding the role of pudendal neuroglia in CSCP syndrome and discussed more options for nerve blocks for CSCP. For microsurgical spermatic cord denervation failure, we included treatment options for salvage ultrasound-guided targeted cryoablation, Botox injections, and posterior-inferior scrotal denervation. Conclusions: Different CSCP subtypes could help general urologists assess the appropriate diagnostic and treatment approaches for scrotal pain management in daily practice.

Indexed as

Chronic scrotal content painMicrodenervation of the spermatic cordOrchialgiaPostinguinal hernia repair painPostvasectomy pain syndromePudendal neuralgiaTestialgiaTesticular painTesticular pain syndrome

Identifiers

PMID40256293
PMCPMC12004993

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.