Evidence map›Paper›PMID 40256256›Full record

ArticleBehavioural neurology2025

Supplementation of the Probiotic LLH135 Reduces Oxidative Stress in a Model of Hemiparkinsonism.

Mario E Flores-Soto, Angelica Y Nápoles-Medina, Aldo R Tejeda-Martínez, Josué R Solís-Pacheco, Verónica Chaparro-Huerta, Juan E Gutiérrez-Sevilla, Blanca R Aguilar-Uscanga

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavioural neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mario E Flores-SotoLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0000-0002-5194-8569
Angelica Y Nápoles-MedinaLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0009-0005-2583-6255
Aldo R Tejeda-MartínezLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0000-0002-0220-5523
Josué R Solís-PachecoLaboratorio de Investigación Leche humana, Departamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0000-0002-6507-0638
Verónica Chaparro-HuertaLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0000-0001-8647-5071
Juan E Gutiérrez-SevillaLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0000-0003-3259-1151
Blanca R Aguilar-UscangaLaboratorio de Investigación Leche humana, Departamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.ORCID https://orcid.org/0000-0002-8100-2598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and neuroinflammation are considered as the two main etiological reasons behind idiopathic Parkinson's disease (PD). Nevertheless, the actual treatments are focused on improving motor symptoms by restoring dopamine (DA) presence, leaving said causes unattended. Probiotics could be a promising strategy for the improvement of these physiological features behind the disease and therefore constitute a complementary treatment for those having PD. This study evaluated the effect of the oral administration of a probiotic bacteria mixture from 3 strains of

Indexed as

Dietary SupplementsOxidative StressParkinsonian DisordersProbioticsAnimalsDisease Models, AnimalLactobacillaceaeLimosilactobacillus fermentumLimosilactobacillus reuteriMaleMiceMice, Inbred C57BLSuperoxide DismutaseSuperoxide DismutasehemiparkinsonismLactobacillusoxidative stressParkinson's diseaseprobiotics

Identifiers

PMID40256256
PMCPMC12006709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.