ArticleJournal of medical physics
Planning and Dosimetry Study of Dynamic Intensity-Modulated Radiotherapy and Volumetric-Modulated Arc Therapy for Carcinomas of the Pharynx Using 6MV Flattening Filter and Flattening Filter-free Beams.
Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Evaluating the trade-off between plan complexity, dosimetric accuracy, and treatment efficiency: Role of aperture shape controller settings in HyperArc for intracranial oligometastases.Precision radiation oncology · 2025Article
- A Comprehensive Dosimetric and Plan Quality Evaluation of Non-coplanar VMAT With Flattening Filter-free Versus Flattened Beams for Hippocampal-Avoidance Whole-Brain Radiotherapy: A Multi-Platform Study on Elekta Infinity and UIH uRT-Linac Systems.Technology in cancer research & treatmentArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to methodically explore and evaluate the effectiveness of volumetric-modulated arc therapy (VMAT) and intensity modulated radiotherapy (IMRT) with both flattened and unflattened 6MV beams for treating pharyngeal carcinomas. Materials and Methods: Twenty patients who had previously undergone treatment for advanced pharyngeal cancer were randomly chosen. They were replanned using a fixed nine-field dynamic IMRT and VMAT with RapidArc using both 6MV flattened and unflattened beams. A total of 80 similar treatment plans were generated for the TrueBeam SVC setup. These plans were assessed for target coverage, maximum and mean doses to the organs at risk, monitor unit (MU), beam-on time, dose to healthy tissue, and other indicators of dose quality. Results: Target coverage was nearly identical across all the techniques. VMAT (6FF and 6FFF) achieved equivalent or superior target coverage while plans give better sparing of mean doses of parotid glands, esophagus, larynx, and maximum dose of the spinal cord while maintaining equivalent maximum dose of the brainstem. The MUs required for VMAT plans were about 4-5 times less than that of IMRT plans, additionally, the 6MV plan shows 20%-30% lesser MU than 6FFF plans in both techniques. Conclusions: VMAT-6FFF shows fewer hot spots in the planning target volume (PTV) high-risk volume and equivalent or higher hot spots in the PTV intermediate-risk and PTV low-risk volumes. In terms of treatment time, VMAT 6FF has fewer MUs than VMAT 6 FFF. Hence, it shows that VMAT 6FF has less treatment time.
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