Evidence map›Paper›PMID 40256136›Full record

ArticleHealth science reports2025

Comprehensive Assessment of Genital Infections and Reproductive Health in Women Visiting a Fertility Clinic in Warangal, India-A Case-Control Study.

Naresh Patnaik, Uttam Sarkar, Malathi Jojula, Hema Vaddiraju, Ruchi Jain Dey

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Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Naresh PatnaikDepartment of Biological Sciences Birla Institute of Technology and Science, Pilani, Hyderabad Campus Hyderabad Telangana State India.
Uttam SarkarDepartment of Animal Genetics and Breeding West Bengal University of Animal and Fishery Sciences West Bengal India.
Malathi JojulaDepartment of Microbiology Sri Shivani College of Pharmacy Warangal Telangana State India.
Hema VaddirajuCurewell Hospital Warangal Telangana State India.
Ruchi Jain DeyDepartment of Biological Sciences Birla Institute of Technology and Science, Pilani, Hyderabad Campus Hyderabad Telangana State India.ORCID 0000-0002-0426-7277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Female infertility is a global health issue however, its link with genital infections is often overlooked due to asymptomatic nature of infections. Delayed diagnosis and treatment due to absence of reliable point-of-care (POC) tools result in long-term pathological consequences and infertility. This pilot-scale study aims to identify the most noteworthy prognostic symptoms of genital infections that exhibit a significant correlation with reproductive tract disorders and infertility. Methods: We designed a detailed questionnaire and conducted a case-control, observational study with 100 female patients, categorized into infertile (n1 = 62) and healthy groups (n2 = 38) followed by statistical analysis. Results: This study highlights an early onset of infertility (18-25 years). Approximately 27% of the infertile female patients are symptomatic for genital infections, and ~42% exhibit menstrual irregularities. Polycystic ovarian syndrome/disease (PCOS/PCOD, ~30%) appears to be the most predominant disorder, followed by endometrial disorders (~10%) and tubal damage (~8%) in infertile patients. A multivariate correlation analysis revealed a highly significant ( Conclusions: Our study shows a significant contribution of genital infections to female infertility. Nevertheless, a substantial 73% of infertile patients are ineligible for confirmatory diagnosis due to the absence of classical infection symptoms. This underscores the pressing requirement for comprehensive screening strategies for timely management of reproductive health and fertility. Patient or Public Contribution: This study was performed in line with the principles of the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) guidelines (Supporting Information 1) [1]. The study was performed following an ethical approval of the Institutional Human Ethics Committee. All individuals who participated in the study were fully informed about various aspects, including the study's objectives, methodologies, sources of funding, potential conflicts of interest, institutional affiliations of the researcher, anticipated benefits, potential risks, and the discomfort they might experience. Their participation was contingent on obtaining their informed consent (See Supporting Information 2 for patient consent form). Furthermore, to safeguard patient confidentiality, we took measures to de-identify patient information. This included the removal of exact ages, which were replaced with age ranges, and the omission of exact dates or photographs during presentation of the data.

Indexed as

endometrial disordersfemale genital tuberculosis (FGTB)female infertilitygenital infectionsmenstrual disordersPCOS & PCOD

Identifiers

PMID40256136
PMCPMC12007467

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